Of 95 reproductive tracts from postpartum bitches, 20 had subinvolution of the placental sites. Grossly, the placental sites were hemorrhagic and about twice the size of normal sites at the same time after parturition. Microscopically, large masses of collagen, hemorrhage and dilated endometrial glands were in the endometrial sites. The myometrium was invaded in many areas by trophoblast-like cells from the endometrium. Variations in the size of placental sites in the same uterus were found in eight cases, and histological variations in the involution process in five. Invasion of the myometrium by trophoblast-like cells four days after parturition was seen in one bitch.
References
1.
Al-BassamM.ThomsonR.G.O'DonnellL.:
Normal post partum involution of the uterus in the dog.Can J Comp Med
(submitted)
2.
AndersonJ.W.:
Ultrastructure of placenta and fetal membranes of the dog.Anat Rec165:
15–36,
1969
3.
ArbeiterK.:
The use of progestins in the treatment of persistent uterine hemorrhage in the postpartum bitch and cow. A clinical report.Theriogenology4:
11–13,
1975
4.
BagshaweK.D.:
Normal trophoblast in choriocarcinoma.In:The Clinical Biology of the Trophoblast and Its Tumors,
pp. 9–27.
Williams and Wilkins,
Baltimore,
1969
5.
BeckA.M.McEnteeK.:
Subinvolution of placental sites in a post partum bitch. A case report.Cornell Vet56:
269–277,
1966
6.
BosuW.T.K.EdqvistL.E.LindbergP.MartinssonK.JohannsonE.D.B.:
The effect of various dosages of lynestrenol on the plasma levels of estrogens and progesterone during the menstrual cycle in the rhesus monkey.Contraception13:
677–684,
1976
7.
BoydJ.D.HamiltonW.J.:
The giant cells of the pregnant human uterus.J Obstet Gynaecol67:
208–218,
1960
8.
DriscollS.C.:
Placental-uterine interrelationships.In:The Uterus,
ed. NorrisHertigAbell,
pp. 213–226.
Williams and Wilkins,
Baltimore,
1973
9.
GlennB.L.:
Subinvolution of placental sites in the bitch.
18th Gaines Veterinary Symposium,
pp. 7–10.
Gaines Dog Research Centre,
White Plains, N. Y.,
1968
10.
HamiltonW.J.BoydJ.D.:
Trophoblast in human utero-placental arteries.Nature212:
906–908,
1966
11.
HamiltonW.J.MossmanH.W.:
The implantation of the blastocyst and the development of the fetal membranes, placenta and decidua.In:Human Embryology,
pp. 83–131.
Williams and Wilkins,
Baltimore,
1973
12.
JohanssonE.D.B.:
Progesterone levels in peripheral plasma during the luteal phase of the normal human menstrual cycle measured by a rapid competitive protein binding technique.Acta Endocrinol61:
592–606,
1969
13.
JubbK.V.F.KennedyP.C.:
The female genital system.In:The Pathology of Domestic Animals,
pp. 487–585,
vol. I.
Academic Press,
New York, San Francisco, London,
1970
14.
KirkR.W.McEnteeK.Bentinck-SmithJ.:
Diseases of the urogenital system.In:Canine Medicine,
ed. Catcott,
pp. 387–418.
American Veterinary Publications,
Santa Barbara, California,
1968
15.
McLarenA.:
Maternal factors in nidation.In:The Early Conceptus, Normal and Abnormal,
ed. Park,
pp. 22–23.
D. C. Thomson and Co.,
Scotland,
1965
16.
McManusJ.F.A.MowryR.W.:
The trichrome technique of Pierre Masson.In:Staining Methods, Histologic and Histochemical,
pp. 234–236.
Harper Medical Division, Harper and Row,
New York, Evanston and London,
1965
17.
MurphyB.E.P.:
Application of the property of protein-binding to the assay of minute quantities of hormones and other substances.Nature201:
679–682,
1964
18.
MurphyB.E.P.:
Some studies of the protein-binding steroids and their application to the routine micro and ultramicro measurement of various steroids in body fluids by competitive protein binding radioassay.J Clin Endocrinol Metab27:
973–990,
1967
19.
OrsiniN.W.:
The trophoblastic giant cells and endovascular cells associated with pregnancy in the hamster, Cricetus auratus.Am J Anat94:
273–331,
1954
20.
SchallW.D.DuncanJ.R.FincoD.R.KnechtC.D.:
Spontaneous recovery after subinvolution of placental sites in a bitch.J Am Vet Med Assoc159:
1780–1782,
1971
