A species of porcine coccidia, Isospora suis, when inoculated into piglets, produced diarrhea, dehydration, weight loss and death. Gross lesions were characterized by a fibrinonecrotic membrane within the jejunum and ileum. Villous atrophy and variable erosion, often with an adhered necrotic membrane, were seen microscopically. Asexual and sexual stages of I. suis were seen within the intestinal epithelium and oocysts were recovered from the feces. The severity of clinical disease and lesions were dose-related.
References
1.
Armed Forces Institute Pathology,
Wednesday slide conference,
No. 5,
1978
2.
BiesterH.E.MurrayC.:
Studies in infectious enteritis of swine. VIII. Isospora suis N. Sp. in swine.J Am Vet Med Assoc85:
207–219,
1934
3.
BergelandM.E.:
Necrotic enteritis in nursing piglets.Proc Am Assoc Vet Lab Diag20:
151–158,
1977
4.
DubeyJ.P.WeisbrodeS.E.RogersW.A.:
Canine coccidiosis attributed to an Isospora ohioenis-like organism: a case report.J Am Vet Med Assoc173:
185–197,
1978
5.
HoeflingD.:
Coccidiosis as a cause of baby pig diarrhea.Proc Am Vet Med Assoc Abstr71,
1978
6.
KentT.H.MoonH.W.:
The comparative pathogenesis of some enteric diseases.Vet Pathol10:
414–469,
1973
7.
MoonH.W.McClurkinA.W.IsaacsonR.E.PohlenzJ.SkartvedtS.M.GilletteK.G.BactzA.L.:
Pathogenic relationships of rotavirus, Escherichia coli, and other agents in mixed infections in calves.J Am Vet Med Assoc173:
577–583,
1978
8.
MoonH.W.NielsonN.D.KramerT.T.:
Experimental enteric colibacillosis of the newborn pig: histopathology of the small intestine and changes in plasma electrolytes.Am J Vet Res31:
103–112,
1970
9.
O'NeillP.A.ParfittJ.W.:
Observations on Isospora suis infection in a minimal disease pig herd.Vet Rec98:
321–323,
1976
10.
SangsterL.T.StuartB.P.WilliamsD.J.BedellD.M.:
Coccidiosis associated with scours in baby pigs.VM/SAC10:
1317–1319,
1978
11.
SoulsbyE.J.L.:
Coccidia of swineinHelminths, Arthropods, and Protozoa of Domesticated Animals,
pp. 636–640;
Williams and Wilkins,
Baltimore,
1968
12.
StewartT.B.SmithW.M.StoneW.M.:
Strongyloidosis: perinatal infection of pigs with Strongyloides ransomi.Georgia Vet21:
13–18,
1969
13.
VetterlingJ.M.:
Coccidia (Protozoa: Eimeriidae) of swine.J Parasitol51:
897–912,
1965
14.
VetterlingJ.M.:
Endogenous cycle of the swine coccidium Eimeria debliecki Douwes, 1921.J Protozool13:
290–300,
1966
15.
VetterlingJ.M.:
Prevalence of coccidia in swine from six localities in the United States.Cornell Vet56:
155–166,
1966
16.
WoodeG.N.CrouchC.F.:
Naturally occurring and experimentally induced rotavirus infections of domestic and laboratory animals.J Am Vet Med Assoc173:
522–526,
1978
