Abstract
Five soft tissue tumors of varied morphology in dogs and cats were classified as malignant fibrous histiocytomas on the basis of their histologic composition. All were composed of varying mixtures of histiocytes and fibroblasts and three contained large multinucleated cells. This giant cell variant of malignant fibrous histiocytoma was seen only in cats. These tumors are comparable to those described in man as malignant fibrous histiocytoma on the basis of the malignant histiocyte and its varied morphology and function.
References
1.
Ackerman
L. V.
Rosai
J.
:
Surgical Pathology ,
pp. 1122 –1124 ;
Mosby ,
St. Louis,
1974
2.
Alexander
J. W.
Rus
R. C.
Dueland
R.
:
Extraskeletal giant cell tumor in a cat.
Vet Med
70 :
1161 –1166 ,
1975
3.
Bednar
B.
:
Storiform neurofibromas of skin, pigmented and non-pigmented.
Cancer
10 :
368 –376 ,
1957
4.
Enzinger
F. M.
:
Epithelioid sarcoma; a sarcoma simulating a granuloma or a carcinoma.
Cancer
26 :
1029 –1041 ,
1970
5.
Guccion
J. G.
Enzinger
F. M.
:
Malignant giant cell tumor of soft parts.
Cancer
29 :
1518 –1529 ,
1972
6.
Kempson
R. L.
Kyriakos
M.
:
Fibroxanthosarcoma of the soft tissues.
Cancer
29 :
961 –976 ,
1972
7.
Leibovitz
A.
Stinson
J. C.
McCombs
W. B.
III
McCoy
C. E.
Mazur
K. C.
Mabry
N. D.
:
Classification of human colorectal adenocarcinoma cell lines.
Cancer Res
36 :
4562 –4569 ,
1976
8.
Nielsen
S. W.
:
Extraskeletal giant cell tumor in a cat.
Cornell Vet
42 :
304 –311 ,
1952
9.
O'Brien
J. E.
Stout
A. P.
:
Malignant fibrous xanthomas.
Cancer
17 :
1445 –1455 ,
1964
10.
Ozello
L.
Stout
A. P.
Murray
M. R.
:
Cultural characteristics of malignant histiocytomas and fibrous xanthomas.
Cancer
16 :
331 –334 ,
1963
11.
Soule
E. H.
Euriquez
P.
:
Atypical fibrous histiocytoma, malignant fibrous histiocytoma, malignant histiocytoma and epithelioid sarcoma.
Cancer
30 :
128 –143 ,
1972
12.
Stout
A. P.
Lattes
R.
:
Tumors of the soft tissues
in
Atlas of Tumor Pathology ,
fasc. I, 2nd ser.,
p. 107 ;
AFIP ,
Washington, D. C.,
1967