Inoculation of lambs either intravenously or intranasally with Histophilus ovis resulted in septicaemia. There was bacterial thrombosis and vasculitis in the liver, lung, kidneys and heart. These lesions were similar to those in natural cases of the disease. With intravenous inoculation of a less virulent isolate there were abscesses in the subcutaneous tissues, muscle fascia and joint bursae.
References
1.
BaynesI.D.SimmonsG.C.:
Ovine epididymitis caused by Actinobacillus seminis N.Sp.Aust Vet J36:
454–459,
1960
2.
BrownR.C.HoppsH.C.:
Staining of bacteria in tissue sections: a reliable Gram stain method.Am J Clin Pathol60:
234–240,
1973
3.
ClaxtonP.D.EverettR.E.:
Recovery of an organism resembling Histophilus ovis from a ram.Aust Vet J42:
457–458,
1966
4.
DoddD.C.HartleyW.J.:
A specific suppurative epididymitis of rams.NZ Vet J3:
105–110,
1955
5.
KaterJ.C.MarshallS.C.HartleyW.C.:
A specific suppurative synovitis and pyaemia in lambs.NZ Vet J10:
143–144,
1962
6.
LivingstoneC.W.HardyW.T.:
Isolation of Actinobacillus seminis from ovine epididymitis.Am J Vet Res25:
660–663,
1964
7.
MilesA.A.MisraS.S.:
as cited by Wilson, G.C.; Miles, A.A.InPrinciples of Bacteriology and Immunity, ed. TopleyWilson; p. 102,
5th ed., Edward Arnold, London, 1964
8.
RahaleyR.S.:
The pathogenicity and bacteriology of Histophilus ovis isolated from sheep in western Victoria. MVSc thesis Melbourne University, Melbourn4, 1977
9.
RahaleyR.S.WhiteW.E.:
Histophilus ovis infection in sheep in western Victoria.Aust Vet J53:
124–127,
1977
10.
RobertsD.S.:
A new pathogen from a ewe with mastitis.Aust Vet J32:
330–332,
1956
11.
Van TonderE.M.:
Infection of rams with Actinobacillus seminis.J S Afr Vet Assoc44:
235–240,
1973
12.
WattD.A.BamfordV.NairnM.E.:
Actinobacillus seminis as a cause of polyarthritis and posthitis in sheep.Aust Vet J46:
515,
1970
13.
WorthingtonR.W.BosmanP.P.:
Isolation of Actinobacillus seminis in South Africa.J S Afr Vet Med Assoc39
(2):81–85,
1968
