Abstract
The gross abnormalities in the intestines of 10 horses with a history of chronic weight loss varied greatly. The principal microscopic change was granulomatous inflammation characterized by lymphocytes, plasma cells, macrophages, epithelioid cells and giant cells. Mycobacterium tuberculosis, avian type, was isolated from the gut content of one horse, but no cause was found in the others. Horses previously reported to have tuberculosis had lesions similar to those described here. These lesions are also similar to those in Crohn's disease of man.
References
1.
Alexander
F.
Davies
M. E.
Muir
A. R.
:
Bacteriophage-like particles in the large intestine of the horse.
Res. vet. Sci.
11 :
592 –593
(1970)
2.
Anderson
W. A. D.
:
Pathology ,
pp. 939 –942
(Mosby ,
St. Louis
1971)
3.
Bach
L. G.
:
Exfoliative cytology of peritoneal fluid in the horse.
Vet. Ann.
14 :
102 –109
(1973)
4.
Baker
R.
:
A case of generalized avian tuberculosis in the horse.
Vet. Rec.
93 :
105 –106
(1973)
5.
Francis
J.
:
Tuberculosis in animals and man ,
pp. 193 –203
(Cassell ,
London
1958)
6.
Gribble
D. H.
:
Granulatous enteritis and intestinal amyloidosis in nonhuman primates.
Abstract. Vet. Pathol.
9 :
81
(1972)
7.
Innes
J. R. M.
:
Tuberculosis in the horse.
Br. vet. J.
105 :
373 –383
(1949)
8.
Kraft
S. C.
Kirsner
J. B.
:
Immunological apparatus of the gut and inflammatory bowel disease.
Gastroenterology
60 :
922 –951
(1971)
9.
Larsen
A. B.
Moon
H. W.
Merkel
R. S.
:
Susceptibility of horses to Mycobacterium paratuberculosis.
Am. J. vet. Res.
33 :
285 –289
(1972)
10.
Laufenstein-Duffy
H.
:
Equine intestinal trichomoniasis.
J. Am. vet. med. Ass.
155 :
1835 –1840
(1969)
11.
Lesslie
I. W.
Davies
D. R. T.
:
Tuberculosis in a horse caused by avian type tubercle bacillus.
Vet. Rec.
70 :
82 –84
(1958)
12.
Luke
D.
:
Tuberculosis in the horse, pig, sheep and goat.
Vet. Rec.
70 :
529 –536
(1958)
13.
Manahan
F. F.
:
Diarrhea in horses with particular reference to a chronic diarrhea syndrome.
Aust. vet. J.
46 :
231 –234
(1970)
14.
M'Fadyean
J.
:
Tuberculosis in the horse caused by bacilli of the avian type.
J. comp. Path. Ther.
31 :
229 –253
(1918)
15.
Mitchell
D. N.
Cannon
P.
Dyer
N. H.
Hinson
K. F. W.
Willoughby
J. M. T.
:
Further observations on Kveim test in Crohn's disease.
Lancet
ii :
496 –498
(1970)
16.
Mitchell
D. N.
Rees
R. J. W.
:
Agent transmissible from Crohn's disease tissue.
Lancet
ii :
168 –171
(1970)
17.
Morganroth
B. S.
Watson
D. W.
:
Sensitivity to atypical mycobacterial antigens in patients with Crohn's disease.
Digest. Dis.
15 :
653 –657
(1970)
18.
Morson
B. C.
Dawson
I. M. P.
:
Gastro-intestinal pathology ,
pp. 261 –279
(Blackwell ,
Oxford
1972)
19.
Nielsen
S. W.
Spratling
F. R.
:
Tuberculosis spondylitis in a horse.
Br. vet. J.
124 :
503 –508
(1968)
20.
Tandon
H. D.
Prakash
A.
:
Pathology of intestinal tuberculosis and its distinction from Crohn's disease.
Gut
13 :
260 –269
(1972)
