An adult female Collie with anorexia, lethargy, posterior limb ataxia, and enterorrhagia had severe leukemia. In the peripheral blood were granulocytes, monocytes and cells with characteristics of both (myelomonocytic intermediates). The dog died within 17 days of the onset of illness. There were widely disseminated green-yellow foci of leukocytes of the same types as in the peripheral blood. A diagnosis of acute myelomonocytic leukemia was made.
References
1.
BeldingH. W.DalandG. A.ParkerF.jr.:
Histiocytic and monocytic leukemia.
Cancer8:
237–252
(1955).
2.
BerkheiserS. W.:
Studies on the comparative morphology of monocytic leukemia, granulocytic leukemia and reticulum cell sarcoma.
Cancer10:
606–616
(1957).
3.
ForknerC. E.:
Clinical and pathological differentiation of the acute Ieukemias with special reference to acute monocytic leukemia.
Arch. intern. Med.53:
1–34
(1934).
4.
LeavellB. S.ThorupO. A.:
Fundamentals of clinical hematology
(Saunders,
Philadelphia1971).
5.
LoebW. F.LamontP. H.CapenC. C.:
Monocytic leukemia in a dog; in
Clarke, Howard and Hackett Myeloproliferative disorders in animals and man
(U. S. Atomic Energy Commission,
Oak Ridge1970).
6.
MedwayW.RappJ. P.:
A case of chronic granulocytic leukemia with thrombocytopenic purpura in a dog.
Cornell Vet.52:
247–255
(1962).
7.
MeierH.:
Neoplastic diseases of the hematopoietic system (so-called leukosis-complex) in dogs.
Zbl. Vet Med.4:
633–688
(1957).
8.
RappaportH.:
Tumors of the hematopoietic system; in
Atlas of tumor pathology,
section III, fasc. 8,
p. 241
(Armed Forces Institute of Pathology,
Washington1966).
9.
RappoportA. E.KugelV. H.:
Monocytic leukemia: a case report illustrating variations in the clinical picture.
Blood2:
332–355
(1947).
10.
RoscherA. A.BoatwrightR. S.KupferH. G.EgdhalR. H.:
Acute myelogenous leukemia with histopathologic studies following total irradiation of a dog.
J. amer. vet. med. Ass.136:
491–500
(1960).