A spontaneous hematopoietic neoplasm in a cotton-top marmoset (Saguinus oedipus) was characterized by perivascular infiltration and invasion of the liver, kidneys, adrenals, spleen, lymph nodes, bone marrow, and lungs by a pleomorphic primitive reticular cell. A significant fraction of the circulating white cells was of the same cell type. The disease was diagnosed as lymphosarcoma of the reticulum-cell type with features similar to viral-induced malignancy previously described.
References
1.
LingemanC. H.ReedR. E.GarnerF. M.:
Spontaneous hematopoietic neoplasms of nonhuman primates.
Review, case report, and comparative studies; in Symposium on comparative morphology of hematopoietic neoplasms. National Cancer Institute Monograph 32,
pp. 157–170
(1969).
2.
HamptonJ. K.:
Laboratory requirements and observations of Oedipomidas oedipus..
Amer. J. phyl. Anthropl.22:
239–243
(1964).
DeinhardtJ. B.DevineJ.PassovoyM.PohlmanR.DeinhardtF.:
Marmosets as laboratory animals. I. Care of marmosets in the laboratory, pathology and outline of statistical evaluation of data.
Lab. Anim. Care17:
11–22
(1967).
5.
GengozianN.:
Marmosets: their potential in experimental medicine.
Ann. N. Y. Acad. Sci.162:
336–362
(1969).
6.
HuntR. D.MeléndezL. V.KingN. W.GilmoreC. E.DanielM. D.WilliamsonM. E.JonesT. C.:
Morphology of a disease with features of malignant lymphoma in marmosets and owl monkeys inoculated with Herpesvirus saimir J.
nat. Cancer Inst.44:
447–465
(1970).
7.
HuntR. D.GarciaF. G.BarahonaH. H.KingN. W.FraserC. E. O.MeléndezL. V.:
Spontaneous Herpesvirus saimiri lymphoma in an owl monkey.
J. infect. Dis127:
723–725
(1973).
8.
KristensenH. K.:
An improved method of decalcification.
Stain Technol.23:
151–154
(1948).
9.
RappaportH.:
Tumors of the hematopoietic system; in
Atlas of tumor pathology, section III,
vol. 8
(AFI of Path.,
Washington1966).
10.
HillW. C. O.:
Reports of the society's prosector.
Proc. zool. Soc., Lond.123:
227
(1953);
124: 309 (1953).