An intracerebral and intraocular neoplasm occurred in a 15-year-old horse. The horse presented with signs of a cerebral space-occupying lesion, blindness, and opacity of the vitreous body. There were a number of cell types within the well-defined tumor, some of which were multinucleate, and some apparently exhibited phagocytosis. The tumor was productive of reticulin fibres. The tumor was diagnosed as a microglioma, an unusual human tumor and one not previously reported in the horse. The intraocular metastasis of the tumor is unique.
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