The toxic effect on pregnant two of Swainsona galegifolia (collected in Australia) and of Astragalus pubentissimus and A. Ientiginosus (collected in the United States) were compared. The signs of intoxication, vacuolar lesions, and clinicopathologic changes were similar. These similarities suggest that the toxic agent or agents may be the same in both genera. Some sheep fed Astragalus aborted and some delivered deformed lambs while those fed Swainsona did not.
References
1.
AdcockJ.I.KeissR.E.;
Locoism in elk.
Bull. Wildlife Dir. Ass.5:
121–124
(1969).
2.
HartleyW.J.KaterJ.C.:
Observations on diseases of the central nervous system of sheep in New Zealand.
New Zeald. vet. J.10:
128–142
(1962).
3.
HuxtableC.R.:
Experimental reproduction and histo-pathology of Swainsona galegifolia poisoning in the Guinea pig.
Austr. J. exp. Biol. Med. Sec.47:
339–347
(1969).
4.
JamesL.F.BennettK.L.ParkerK.G.KeelerR.F.BinnsW.LindsayB:
Loco plant poisoning in sheep.
J. Range Mgmt.21:
360–365.
5.
JamesL.F.KeelerR.F.BinnsW.:
Sequence in the abortive and teratogenic effects of locoweed fed to sheep.
Amtr. J. vet. Res.30:
377–380
(1969).
6.
JamesL.F.ShupeJ.L.BinnsW.KeelerR.F.:
Abortive and teratogenic effects of locowced on sheep and cattle.
Amer. J. vet. Res.28:
1379–1388
(1967).
7.
KeelerR.F.JamesL.F.BinnsW.ShupeJ.L.;
An apparent relationship between locoism and lathyrism.
Canad. J. comp. Med.31:
334–341
(1967).
8.
KingsburyJ.M.:
Poisonous Plants of the United States and Canada
(Prentice-Hall.Englenwood Cliffs1964).
9.
LawsL.AnsoonR.B.:
Neuronopathy in sheep fed Swainsona luteola and S. galegifolia.
Austr. vet. J.44:
447–452
(1968).
10.
MaidenJ.H.:
Plants Reputed to be Poisonous to Livestock in Australia.
Dept. Agric. New Soutb Wales. Misc. Pub.477:
15–16
(1901).
11.
MarshC.D.:
The Locowced Disease of the Plains,U.S.D.A,
Bur. Animal Industry Bull.112
(1909).
12.
MarshC.D.ClawsonA.B.EgglestonW.W.:
The Loconweed Disease.
U.S.D.A. Bulletin1050
(1919)
[Revised by A.B. Flawson (1936)].
13.
MartinC.J.:
Report on an investigation into the effects of Darling pea (Swainsoma galegifolia) upon sheep.
Agrie. Gas. New South Wales8:
366
(1898)
[Quoted by A.C. Crawford in Barium, a cause of the locowced disease. U.S. D.A. Bur. Plant Industry Bull. 129: 16 (1908)].