Twenty of 24 dogs with mastocytoma had ulcers of the gastroduodenal mucosa. The ulcers were more frequent in the stomach, less frequent in the duodenum. Perforating ulcers caused death in 3 dogs. Vascular lesions were frequent in these dogs, and it was considered that the vascular alterations may have contributed to the gastroduodenal ulceration associated with mast-cell neoplasms.
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