The clinical course, radiographic description, hematologic changes, histopathologic evaluations, and electron microscopic findings are presented on an osteogenic sarcoma involving the frontal bone of an adult female Macaca mulatta, with metastases to the lungs and adrenal. In addition, this monkey also had a subcutaneous lipoma of the leg, a hemangioma of the liver, and a renal adenocarcinoma.
References
1.
AckermanL.V.SpjutH.J.:
Tumors of Bone and Cartilage. Section II – Fascicle 4
(Armed Forces Institute of Pathology,
Washington, D. C.1953)
2.
BraggH.J.:
Neoplams in the lower primate, with a description of an osteogenic sarcoma of the jaw in a Macacus rhesus.Amer. J. Cancer15:
2143–2148
(1931)
3.
BrodeyR.S.SauerR.M.MedwayW.:
Canine bone neoplasms.J. amer. vet. med. Ass.143:
471–495
(1963)
4.
CarlsonW.D.:
Veterinary Radiology,
pp. 186
(Lea and Febiger,
Philadelphia1961)
5.
CaulfieldJ.B.:
Effects of varying the vehicle for OsO4 in tissues.J. biohpys. biochem. Cytol.3:
827–829
(1957)
6.
ChapmanW.L.Jr.AllenJ.R.: Unpublished observation. Wisconsin Regional Primate Research Center
(1966)
7.
EdmondsonH.A.:
Tumors of the Liver and Intrahepatic Bile Ducts. Section VII – Fascicle 25
(Armed Forces Institute of Pathology,
Washington, D. C.1958)
8.
JohnsonL.E.GayJ.R.BootheH.W.:
Removal of osteosarcoma of the skull followed by roentgen therapy.J. amer. vet. med. Ass.120:
73–75
(1952)
9.
JubbK. V. F.KennedyP.C.:
Pathology of Domestic Animals,
Vol. I
(Academic Press,
New York1963)
10.
JungherrE.:
Tumors and tumor-like condition in monkeys.Ann. N. Y. Acad. Sci.108:
777–792
(1963)
11.
KentS.P.:
Spontaneous and induced malignant neoplasms in monkeys.Ann. N. Y. Acad. Sci.85:
819–827
(1960)
12.
KentS.P.PickeringJ.E.:
Neoplasms in monkeys (Macaca mulatto): Spontaneous and irradiation-induced.Cancer11:
138–147
(1958)
13.
LichtensteinL.:
Bone Tumors,
3rd ed.
(The C. V. Mosby Company,
St. Louis1965)
14.
LombardL.S.WitteE.J.:
Frequency and types of tumors in mammals and birds of the Philadelphia Zoological Gardens.Cancer Res.19:
127–141
(1959)
15.
L'ucké“B.SchlumbergerH.G.:
Tumors of the Kidney, Renal Pelvis and Ureter. Section VIII – Fascicle 30
(Armed Forces Institute of Pathology,
Washington, D. C.1957)
16.
MollenhauerH.H.:
Plastic embedding mixtures for use in electron microscopy.J. stain Tech.39:
111–114
(1964)
17.
MoultonJ.E.:
Tumors in Domestic Animals,
pp. 33,
147
(University of California Press,
Los Angeles,1961)
18.
NewberneJ.W.RobinsonV.B.:
Spontaneous tumors in primates – A report of two cases with notes on the apparent low incidence of neoplasms in subhuman primates.Amer. J. vet. Res.21:
150–155
(1960)
19.
OwenL.N.:
An account of multiple osteosarcomata of bone in dogs having multicentric or metastatic origin.Brit. J. Radiol.38:
520–526
(1965)
20.
PetrovN.N.:
Resultaty eksperimentov po kantserogenezu u obez' ian za 20 let raboty (1939–1960).Vop. Onkol.6(12):
3–8
(1960).
(Translation appears in Prob. Oncol.6: 1709–1715 (1960)
21.
RatcliffeH.L.:
Incidence and nature of tumors in captive wild mammals and birds.Amer. J. Cancer17:
116–135
(1933)
22.
RatcliffeH.L.:
Familial occurrence of renal carcinoma in rhesus monkeys (Macaca mulatta).Amer. J. Path.16:
619–624
(1940)
23.
RatcliffeH.L.:
Deaths and important diseases
(70th Annual Rep. Penrose Res. Lab.) Zool. Soc. Phila.11–25
(1942)
24.
RobbinsL.:
Textbook of Pathology,
3rd ed.
(W. B. Saunders Co.,
Philadelphia1967)
25.
ScottH.H.:
Report on the deaths occurring in the Society's Gardens during the year 1927.Proc. zool. Soc. Lond.98:
81–119
(1928)
26.
SmithH.A.JonesT.C.:
Veterinary Pathology,
3rd ed.
(Lea and Febiger,
Philadelphia1966)
27.
StoutA.P.:
Tumors of the Soft Tissues. Section II – Fascicle 5
(Armed Forces Institute of Pathology,
Washington, D. C.1953)
28.
VadovaA.V.Gel'shteinV.I.:
Spontaneous tumors in lower catarrhine monkeys according to the data of the monkey breeding station of the Sukhumi Medico-Biological Station,
pp. 137–163.
In: Theoretical and Practical Questions of Medicine and Biology in Experiments on Monkeys.
UtkinL.A.
(Pergamon,
London1960)
29.
WarrenS.MeissnerW.A.:
Tumors of the Thyroid Gland. Section IV – Fascicle 14
(Armed Forces Institute of Pathology,
Washington, D. C.1953)
30.
WarwickR.A.:
Sarcoma of bone in a ring-tailed lemur (Lemur catta).J. Path. Bact.63:
499–501. pls. 86–88
(1951)
