A spontaneous outbreak of infection with C. kutscheri occurred in a commercial rat colony. Clinical signs were emaciation, hyperpnea, nasal and ocular encrustations, humping of the back, sluggishness, and roughness of the hair coat. Caseopurulent foci, 1 to 15 mm in diameter, occurred, primarily in the lungs and occasionally in the liver, kidneys, and subcutis. Corynebacterium kutscheri was consistently isolated from organs with lesions. Typical lesions were experimentally reproduced in some, but not all, rats inoculated by the intranasal, intraperitoneal, and oral routes with cultures of C. kutscheri.
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