The pathological features of spontaneous herpes-T infection in 6 owl monkeys (Aotus trivirgatus) were characterized by the presence of intranuclear inclusion bodies in epithelial and mesenchymal cells associated with necrosis of the skin, oral mucous membranes, esophagus, small intestine, cecum, colon, nasal mucous membranes, larynx, trachea, lung, liver, spleen, lymph nodes, adrenal gland, and bone marrow. The inclusion bodies and the lesions are similar to herpes virus infections of other animal species. A virus was isolated from 5 monkeys, which on the basis of serum neutralization tests in vitro was identified as herpes-T.
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