The pathogenesis of the ocular lesions that occur during convalescence from infectious canine hepatitis was studied in susceptible dogs by passive sensitization, reverse-passive sensitization, and by intraocular inoculation with virus-antibody precipitate suspensions. By these methods it was demonstrated that iridocyclitis and corneal opacification could be produced. These lesions resembled those that occur naturally in this disease. It was concluded that the natural ocular lesions that follow infectious canine hepatitis are a consequence of Arthus-type hypersensitivity reactions.
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