Bilateral renal hypoplasia of the pig is described and is compared with a previous description. The defect was observed in 19 piglets out of a total of 73 born in eight litters, sired by one Large White boar. Twelve affected piglets died at or soon after birth and 7 died between the ages of 11 and 69 days. Inheritance by a simple autosomal recessive factor is suggested by the evidence.
Grossly the condition was characterized by varying degrees of hypoplasia and persistence of foetal lobulation. Microscopically, the dominant feature was the poor development of the collecting tubule system. It is concluded that the basic defect is a failure of development of mesonephric mesenchyme.
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