A five year old cat was presented with signs of an acute afebrile debilatiting disease of one week's duration. There was loss of appetite, listlessness and general malaise. Treatment was ineffectual, the cat became moribund and was humanely killed 12 days after the first admission. The clinical course, laboratory findings including examination of the cells of the blood, bone marrow and spleen suggested an erythropoietic malignancy similar to Di Guglielmo's syndrome in man.
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