The granuloma is a significant form of inflammatory response in chickens, and the various bacteria, fungi, viruses and protozoa which elicit granulomas are discussed. The granuloma is a frequent and important lesion of the lung in chickens, the inciting infection reaching this organ by the hematogenous or aerogenous route. The anatomy of the avian respiratory tract influences the pathogenesis of granulomatous inflammation; these anatomic features are described. It has not yet been determined whether any pulmonary necrosis, given sufficient time, can develop into a granuloma, or whether the process requires the participation of certain specific infectious agents.
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