Development of hypersensitivity reactions to carboplatin (CP) during cancer treatment makes optimal chemotherapy difficult to achieve. Many approaches have previously been used following the development of reactions to CP. We report on a patient with ovarian cancer who developed a hypersensitivity reaction to CP. The patient was successfully treated following replacement of carboplatin with cisplatin.
PepysJ.: Allergy of the respiratory tract to low molecular weight agents.Hndb. Exp. Pharmacol., 63: 163–185, 1983.
3.
ShlebakA.A., ClarkP.I., GreenJ.A.: Hypersensitivity and cross-reactivity to cisplatin and analogues.Cancer Chemother. Pharmacol., 35: 349–351, 1995.
4.
ShukunamiK., KurokawaT., KawakamiY., KuboM., KotsujiF.: Hypersensitivity reactions to intraperitoneal administration of carboplatin in ovarian cancer: the first report of a case.Gynecol. Oncol., 72: 431–432, 1999.
5.
SoodA.K., GelderM.S., HuangS.W., MorganL.S.: Anaphylaxis to carboplatin following multiple previous uncomplicated courses.Gynecol. Oncol., 57: 131–132, 1995.