Advanced colorectal cancer meta-analysis project.Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: evidence of terms of response rate.J. Clin. Oncol., 10: 896–903, 1992.
2.
DoroshowJ.H., MulthaufP., LeongL., MargolinK., LitchfieldT., AkmanS., CarrB., BertrandM., GolbergD., BlaynayD., OdujinrinO., DelapR., ShusterJ., NewmanE.: Prospective randomized comparison of fluorouracil and high-dose continuous infusion leucovorin calcium for the treatment of advanced measurable colorectal cancer in patients previously exposed to chemotherapy.J. Clin. Oncol., 7: 491–501, 1990.
3.
EinhornL.H.: Improvements in fluorouracil chemotherapy?J. Clin. Oncol., 7: 1377–1379, 1989.
4.
ErlichmanC.: Development of new thymidylate synthase inhibitors.ASCO Educational Book, pp. 98–101, 1995.
5.
ErnstoffM.S., LemberskyB.C., KirkwoodJ.M.: Fluorouracil, interferon-alpha, and colon cancer: rational pursuit of synergism between antimetabolites and biologicals.J. Clin. Oncol., 7: 1764–1765, 1989.
6.
GerstnerJ., O'ConnellM.J., WieandH.S., BurokerT.R., KrookJ.: A prospectively randomized clinical trial compared 5-FU combined with either high or low dose leucovorin for the treatment of advanced colorectal cancer.Proc. ASCO,10: 134, 1991.
7.
GrecoF.A., FiglinR., YorkM., EinhornL., SchilskyR., MarshallE.M., BuysS.S., FroimtchukM.J., SchullerJ., SchuchterL., BuyseM., RitterL., ManA., YapA.K.L.: Phase III randomized study to compare interferon alfa-2a in combination with fluorouracil versus fluorouracil alone in patients with advanced colorectal cancer.J. Clin. Oncol., 14: 2674–2681, 1996.
8.
KemenyN., KelsenD., DerbyS.: Combination 5-fluorouracil and recombinant alpha-interferon in advanced colorectal carcinoma: activity but significant toxicity.Proc. Am. Soc. Clin. Oncol.,9: 109, 1990.
9.
KennedyP., PresantC.A., BlayneyD.: Sandostatin therapy for chemoterapy and radiotherapy related diarrhea.Proc. Am. Soc. Clin. Oncol.,9: 324, 1990.
10.
LeichmanC.G., FlemingT.R., MuggiaF.M., TangenC.M., ArdalanB., DoroshowJ.H., MeyersF.J., HolcombeR.F., WeissG.R., MangalikA., MacdonaldJ.S.: Phase II study of fluorouracil and its modulation in advanced colorectal cancer: A Southwest Oncology Group Study.J. Clin. Oncol., 13: 1303–1311, 1995.
11.
LokichJ.J., AhlgrenJ.D., GulloJ.J., PhilipsJ.A., FryerJ.G.: A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: a Mid-Atlantic Oncology Program Study.J. Clin. Oncol., 7: 425–432, 1989.
Nordic Gastrointestinal Tumor Adjuvant Therapy Group:Expectancy or primary chemotherapy in patients with advanced asymptomatic colorectal cancer.J. Clin. Oncol., 6: 904–911, 1992.
14.
O'DwyerP.J., PaulA., WalczakJ., WeinerL.M., LitwinS., ComisR.L.: Phase II study of biochemical modulation of fluorouracil by low-dose PALA in patients with colorectal cancer.J. Clin. Oncol., 8: 1497–1503, 1990.
15.
O'DwyerP.J., RyanL.M., ValoneF.H., HinesJ.D., ArbuckS.G., WadlerS., HallerD.G., MayerR.J., BensonA.B.: Phase III trial of biochemical modulation of 5-fluorouracil by iv or oral leucovorin or by interferon in advanced colorectal cancer.An ECOG/CALGB phase III Trial. Proc. Am. Soc. Clin. Oncol.,15: 207, 1996.
16.
OgawaM.: New systemic drugs in the treatment of gastrointestinal cancer.Curr. Opin. Oncol., 8: 317–320, 1996.
17.
PazdurR., AbbruzzeseJ., FaintuchJ., AjaniJ., PattY., JacksonD., MarkowitzA., WinnR., GuttermanJ., LevinB.: Phase II study of recombinant interferon alpha and 5-fluorouracil in patients with advanced colorectal cancer.Proc. Am. Soc. Clin. Oncol.,9: 117, 1990.
18.
PetrelliN., DouglassH.Q.Jr., HerreraL., RusselD., StableinD.M., BrucknerH.W., MayerR.J., SchinellaR., GreenM.D., MuggiaF.M., MegibowA., GreenwaldE.S., BukowskiR.M., HarrisJ., LevinB., GaynorE., LoutfiA., KelsenM., BarkinJ.S., BenedettoP., WoolleyP.V., NautaR., WeaverD.W., LeichmanL.: The modulation of fluorouracil with leucovorin in metastatic colorectal carcinoma: a prospective randomized phase III trial.J. Clin. Oncol., 7: 1419–1426, 1989.
19.
PoonM.A., O'ConnellM.J., MoertelC.G., WieandH.S., CullimanS.A., EversonL.K., KrookJ.E., MailliardJ.A., LaurieJ.A., TschetterL.K., WiesenfeldM.: Biochemical modulation of fluorouracil: evidence of significant improvement in survival and quality of life in patients with advanced colorectal cancer.J. Clin. Oncol., 7: 1407–1418, 1989.
20.
SeymourM.T., SlevinM.L., KerrD., JamesR.D., LedermannJ.A., PerrenT.J., McAdamW.A.F., HarperP.G., NeoptolemosJ.P., NicholsonM., DuffyA.M., StephensR.J., StenningS.P., TaylorI.: Randomized trial assessing the addition of interferon α-2a to fluorouracil and leucovorin in advanced colorectal cancer.J. Clin. Oncol., 14: 2280–2288, 1996.
21.
WadlerS., SchwartzE.L., GoldmanM., LyverA., RaderM., ZimmermanM., ItraL., WeinbergV., WiernikP.H.: Fluorouracil and recombinant alpha-2a-interferon: an active regimen against advanced colorectal carcinoma.J. Clin. Oncol., 7: 1769–1775, 1989.