The authors describe the case of a 71-year-old man without signs of phacomatosis with a history of progressive psychomotory lowering and two simultaneous tumors of the olfactory groove and of the cerebellopontine angle, as demonstrated by CT scans. Histologic examinations showed the lesions to be a meningioma and a neurinoma. The rarity and the possible pathogenesis of this association are discussed.
AndrioliG.C., ZuccarelloM., ScanariniM., d'AvellaD.: Concurrent primary intracranial tumours of different histogenesis. Acta Neuropathol., Suppl. 7: 111–115, 1981.
2.
ChaparroM.J., YoungR.F., SmithM., ChoiB.H.: Multiple spinal meningiomas: a case of 47 distinct lesions in the absence of neurofibromatosis or identified chromosomal abnormality. Neurosurgery, 32: 298–302, 1993.
3.
CohnheimJ.: Vorlesungen uber allgemeine. Pathologie, pp. 57–62, VA Hirschwald, Berlin, 1878.
4.
DeenH.G., LawsE.R.: Multiple primary brain tumors of different cell types. Neurosurgery, 8: 20–25, 1981.
5.
DellemanJ.W., De JongJ.G.Y., BleekerG.M.: Meningiomas in five members of a family over two generations, in one member simultaneously with acoustic neurinoma. Neurology, 28: 567–570, 1978.
6.
EljamelM.S.M., FoyP.M.: Multiple meningiomas and their relation to neurofibromatosis: review of the literature and report of seven cases. Surg. Neurol., 32: 131–136, 1989.
7.
FeiginI.: Mixed mesenchymal tumors: meningioma and nerve sheath tumor. J. Neuropathol. Exp. Neurol., 37: 251–253, 1978.
8.
GokalpH.Z., ErdoganA., EgemenN., NaderiS.: Multiple intracranial tumors of different cell types. Neurosurgery, 27: 463–466, 1990.
9.
KawaguchiS., OhnishiH., YuasaT., HashimotoH., Hiramat-suK.: Multiple primary intracranial tumors of different cell types. Case report. Neurol. Med. Chir. (Tokyo), 26: 639–643, 1986.
10.
MadonickM.J., ShapiroJ.H., TorackR.M.: Multiple diverse primary brain tumors. Report of a case with review of literature. Neurology, 11: 430–436, 1961.
11.
MartuzaR.L., EldridgeR.: Neurofibromatosis 2 (bilateral acoustic neurofibromatosis). N. Engl. J. Med., 318: 684–688, 1988.
12.
O'ConnellJ.E.A.: Intracranial meningiomata associated with other tumours involving the central nervous system. Br. J. Surg., 48: 373–383, 1961.
13.
RiccardiV.M.: von Recklinghausen's neurofibromatosis. N. Engl. J. Med., 305: 1617–1627, 1981.
14.
RussellD.S., RubinsteinL.J.: Pathology of tumours of the nervous system, p. 64, Edward Arnold, London, 1971.
15.
SaharA., StreiflerH.: Multiple intracranial tumors of diverse origin. Report of a case with review of literature. Neurochi-rurgia, 9: 18–27, 1966.
16.
ScheggJ.F., de TriboletN.: Neurinoma of the facial nerve associated with a parietal meningioma. Surg. Neurol., 21: 19–22, 1984.
17.
SharmaS., RayR.C., HassanM.I.: Primary intraorbital meningioma and schwannoma: a rare association. Indian J. Ophthalmol., 37: 194–195, 1989.
18.
ShuangshotiH., NetskyM.G., JaneJ.A.: Neoplasms of mixed mesenchymal and neuroepithelial type, with consideration of the relationship between meningioma and neurilem-moma. J. Neurol. Sci., 14: 277–291, 1971.
19.
StumpfD., AlksneJ., AnnegersJ.: Neurofibromatosis conference statement. National Institutes of Health Consensus Development Conference. Arch. Neurol., 45: 575–578, 1988.
20.
SuzukiS., KatakuraR., KatoS., SuzukiJ.: Adjacent meningioma and astrocytoma in the brain. Case report. Neurol. Med. Chir. (Tokyo), 27: 325–328, 1987.
21.
ThomassinJ.M., PelletW., AbramD., KorchiaD.: Tumeurs de l'angle ponto-cerebelleux. Association fortuite d'un me-ningiome et d'un neurinome. Ann. Oto. Laryngol. (Paris), 108: 248–252, 1991.
22.
WilmsG., PletsC., GoossensL., GoffinJ., VanwambekeK.: The radiological differentiation of acoustic neurinoma and meningioma occurring together in the cerebellopontine angle. Neurosurgery, 30: 443–446, 1992.
23.
WilsonP.J.E., AshleyJ.B.: Meningioma after contralateral hemispherectomy for malignant glioma: case report. J. Neurol. Neurosurg. Psychiatry, 38: 493–499, 1975.