The onset of oncocytic neoplasms in the ocular area is exceptional. A rare case of oxyphil cell adenoma of the lacrimal caruncle in an 81-year-old woman is presented. In addition, 49 cases from literature were reviewed. The anatomo-clinical profile of this benign small tumor is drawn up: a slowly growing tumor, generally occuring in the caruncle of elderly women, which is characterized by a uniform population of epithelial cells with eosinophilic finely-granular cytoplasm containing large numbers of mitochondria. The histogenetic problem of this tumor is briefly discussed.
Get full access to this article
View all access options for this article.
References
1.
BarcaL.: Adenoma a oncociti del sacco lacrimale. Ann. Oftalmol. Clin. Ocul., 97: 233–234, 1971.
2.
BiggsS.L.FontR.L.: Oncocytic lesion of the caruncle and other adnexa. Arch. Ophthalmol., 95: 474–478, 1977.
3.
ChangW.J.NowinskiT.S.EagleR.C.: A large oncocytoma of the caruncle. Arch. Ophthalmol., 113: 382, 1995.
4.
DeutschA.R.DuckworthJ.K.: Onkocytoma (oxyphyl adenoma) of the caruncle. Am. J. Ophthalmol., 64: 458–461, 1967.
5.
FreddoT.F.LeibowitzH.M.: Oncocytoma of the caruncle: a case report and ultrastructural study. Cornea, 10: 175–182, 1991.
6.
GreerC.H.: Oxyphyl cell adenoma of the lacrimal caruncle. Br. J. Ophthalmol., 53: 198–202, 1969.
7.
HamperlH.: Benign and malignant oncocytoma. Cancer, 15: 1019–1027, 1962.
8.
HeathcoteJ.C.KumaloT.G.WillisN.R.MillsD.M.: Oncocytoma of the lacrimal caruncle. Can. J. Ophthalmol., 21: 178–183, 1986.
9.
JaffføR.N.: Adenolymphoma (onkocytoma) of parotid gland. Am. J. Cancer, 16: 1415–1423, 1932.
OstrachowiczM.MeyerJ.: A case of oncocytic adenoma (oxyphilic granulocellular adenoma) of the lacrimal sac. Klin. Oczna., 33: 197–202, 1963.
17.
PeretzW.EttinghausenS.E.GrayG.F.: Oncocytic adenocarcinoma of the lacrimal sac. Arch. Ophthalmol., 96: 303–304, 1978.
18.
RennieI.G.: Oncocytomas (oxyphil adenomas) of the lacrimal caruncle. Br. J. Ophthalmol., 64: 935–939, 1980.
19.
RogersI.R.JakobiecF.A.KrebsW.HornblassA.GingoldM.: Papillary oncocytoma of the eyelid. A previously undescribed tumor of apocrine gland origin. Ophthalmology, 95: 1071–1076, 1988.
20.
SacksE.JakobieicF.A.McMillanR.FraunfelderF.IwamotoT.: Multiple bilateral apocrine cystadenomas of the lower eyelids: light and electron microscopic studies. Ophthalmology, 94: 65–71, 1987.
21.
SantosA.Gomez-LealA.: Lesions of the lacrimal caruncle. Clinicopathologic features. Ophthalmology, 101: 943–949, 1994.
22.
ShieldsC.L.ShieldsJ.A.WhiteD.AugsburgerJ.J.: Types and frequency of lesions of the caruncle. Am. J. Ophthalmol., 102:771–778,1986.
23.
SlaterD.N.CottonD.W.K.AzzopardiJ.G.: Oncocytic glomus tumour: a new variant. Histopathology, 11: 523–531, 1987.
24.
ThallerV.T.CollinJ.R.O.McCartneyA.C.E.: Oncocytoma of the eyelid: a case report. Br. J. Ophthalmol., 71: 753–756, 1987.
25.
WilkersonJ.A.WinquistW.D.: Bilateral papillary cystoadenoma of the lacrimal caruncle. Arch. Pathol., 88: 540–552, 1969.
