After conservative treatment of breast carcinoma (quadran-tectomy and axillary dissection, plus radiotherapy), the growth of an angiosarcoma in the irradiated skin is a very rare event. We report a case, developed in the breast skin 62 months after the irradiation, and discuss the therapeutic possibilities and the role of follow-up in these patients.
BadweR.A., HanbyA.M., FentimanI.S., ChaudaryM.A.Angiosarcoma of the skin overlying an irradiated breast.Breast Cancer Res and Treat, 19: 69–72, 1991.
2.
BobinY., DolbeauD., BesnardC., MignotteH., RivoireM., ZlatoffP.: Angiosarcoma of the breast. A report of four cases and review of the literature.Bull Cancer, 78(11): 1037–1044, 1991.
EdeikenS., RussoD.P., KnechtJ., ParryL.A., ThompsonR.M., Angiosarcoma after tylectomy and radiation therapy for carcinoma of the breast.Cancer, 70: 644–647, 1992.
5.
GivensS., EllenbroekN.A., ButlerJ.J., LibshitzH.I., HortobagyiG.N., McNeeseM.D.: Angiosarcoma arising in an irradiated breast: a case report and review of the literature.Cancer, 64: 2214–2216, 1989.
6.
HamelsJ., BlondiauP., MirgauxM.: Cutaneous angiosarcoma arising in a mastectomy scar after therapeutic irradiation.Cancer, 68: 353–356, 1981.
7.
HunterT.B., MartinP.C., DietzenC.D., TylerL.T.: Angiosarcoma of the breast: two case reports and review of the literature.Cancer56: 2099–2106, 1985.
8.
KutenA., SapirD., CohenY., HaimN., BorovikR., RobinsonE.: Postirradiation soft tissue sarcoma occuring in breast cancer patients: report of seven cases and results of combination chemotherapy.J. Surg. Oncol.28: 168–171, 1985.
9.
LibermanL., DershawD.D., KaufmanR.J., RosenP.P.: Angiosarcoma of the breast.Radiology, 183(3): 649–654, 1992.
10.
MaddoxJ.C., EvensH.L.: Angiosarcoma of skin and soft tissue. A study of forty-four cases.Cancer, 48: 1907–1921, 1981.
11.
MalavaudB., PessonnierA., MartelP., RocheH., MarquesB.: Angiosarcoma of the breast. A clinical case.J. Gynecol. Obstet. Biol. Reprod. Paris., 18(2): 173–176, 1989 (ABS).
12.
McConnellA.H., HaslamP.: Angiosarcoma in postmastectomy lymphoedema: a report of five cases and review of literature.Br. J. Surg., 46: 322–332, 1959 (ABS).
13.
MoskalukC.A., MerinoM.J., DanforthD.N., MedeirosL.J.: Low grade angiosarcoma of the skin of the breast: a complication of lumpectomy and radiation therapy for breast carcinoma.Hum. Pathol.23: 710–714, 1992.
14.
RubinE., MaddoxW.A., MazumM.T.: Cutaneous angiosarcoma of the breast seven years after lumpectomy and radiation therapy.Radiology, 174: 258–264, 1990.
15.
StewartF.W., TrevesN.: Lymphangiosarcoma in postmastectomy lymphedema: a report of six cases in elephantiasis chirurgica.Cancer, 1: 64–81, 1948.
16.
StokkelM.P.M., PeterseH.L.: Angiosarcoma of the breast after lumpectomy and radiation therapy for adenocarcinoma.Cancer, 69: 2965–2968, 1992.
17.
WijnmaalenA., Van OoijenB., Van GeelB., Henzen-LongmansS.C., Treurniet-DonkerA.D.: Angiosarcoma of the breast following lumpectomy, axillary lymph node dissection, and radiotherapy for primary breast cancer: three case reports and a review of the literature.Int. J. Radiat. Oncol. Biol. Phys, 26: 135–139, 1993.
18.
ZucaliR., MersonM., PlacucciM., Di PalmaS., VeronesiU.: Soft tissue sarcoma of the breast after conservative surgery and irradiation for early mammary cancer.Radiother. Oncol.30: 271–273, 1994.