A case of oat-cell carcinoma arising in the pericardium of a 51-year-old woman is described. The patient had multiple nodes; the largest was 2 × 1 cm. Two years later the patient presented with a tumor on her lower gum; this measured 2 mm and had similar characteristics to the previous one. The immunohistochemical study showed strong positivity for neuron-specific enolase. From review of the literature, it may be concluded that this is the first report of oat-cell carcinoma occurring in the pericardium.
BouvierD.P., BellB.: Small cell carcinoma of the pleura.South. Med. J., 82: 1437–1438, 1989.
2.
CorrinB., GilbyE.D., JonesN.F., PatrickJ.: Oat cell carcinoma of the pancreas with ectopic ACTH secretion.Cancer, 31: 1523–1527, 1976.
3.
CramerS.F., AikawaM.: Neurosecretory granules in small cell invasive carcinoma of the bladder.Cancer, 47: 724–730, 1981.
4.
DavisB.H., LudwingM.E., ColeS.R., PastuszakW.T.: Small cell neuroendocrine carcinoma of the urinary bladder: Report of three cases with ultrastructural analysis.Ultrastruct. Pathol., 4: 197–204, 1983.
EimotoT., HayakawaH.: Oat cell carcinoma of the stomach.Pathol. Res. Pract., 168: 229–236, 1980.
7.
HoK.J., HerreraG.A., JonesJ.M., AlexanderC.B.: Small cell carcinoma of the esophagus: Evidence for a unified histogenesis.Hum. Pathol., 15: 460–468, 1984.
8.
HsuS.M., RaineL., FangerH.: Use of avidin-biotin peroxidase complex (ABC) in immunoperoxidase techniques: A comparison between ABC and unlabeled antibody (PAP) procedures.J. Histochem. Cytochem., 29: 577–580, 1981.
KraemerB.B., MackayB., BatsakisJ.G.: Small cell carcinomas of the parotid gland: A clinicopathologic study of three cases.Cancer, 52: 2115–2121, 1983.
11.
MillsS.E., AllenM.S., CohenA.R.: Small-cell undifferentiated carcinoma of the colon: A clinicopathologic study of five cases and their association with colonic adenomas.Am. J. Surg. Pathol., 7: 643–651, 1983.
12.
MillsS.E., CooperP.H., GarlandT.A., JohnsM.E.: Small cell undifferentiated carcinoma of the larynx: Report of two patients and review of 13 additional cases.Cancer, 51: 116–120, 1983.
13.
OlsonN., TwiggsL., SibbleyR.: Small cell carcinoma of the endometrium: Light microscopic and ultrastructural study of a case.Cancer, 50: 760–765, 1982.
14.
PartanenS., AsikainenU.: Oat cell carcinoma of the urinary bladder with ectopic adrenotropic hormone production.Hum. Pathol., 16: 313–315, 1985.
15.
PearseA.G.E.: The diffuse neuroendocrine system: an extension of the APUD concept. In: Endocrinology.TalyorS. (Ed.), p. 145, Heinemann, London, 1972.
16.
PearseA.G.E., TakorT.: Embryology of the diffuse neuroendocrine system and its relationship to the common peptides.Fed. Proc., 38: 2288–2294, 1979.
17.
RemickJ.C., HafezG.R., CarboneP.P.: Extrapulmonary small-cell carcinoma. A review of the literature with emphasis on therapy and outcome.Medicine, 66: 457–471, 1987.
18.
RichardsonR.L., WeilandL.H.: Undifferentiated small cell carcinomas in extrapulmonary sites.Semin. Oncol., 9: 484–496, 1982.
19.
RosaiJ., LevineG., WeberW.R., HighE.: Carcinoid tumors and oat cell carcinomas of the thymus.Pathol. Annu., 11: 201–226, 1976.
20.
SilvaE.G., OrdóñezN.G., LechagoJ.: Immunohistochemical studies in endocrine carcinoma of the skin.Am. J. Clin. Pathol., 81: 558–562, 1984.
21.
TaxyJ.S., EttingerD.S., WharmamM.D.: Primary small cell carcinoma of the skin.Cancer, 46: 2308–2311, 1980.
22.
Van Der GaastA., VerweyJ., PrinsE., SplinterT.A.: Chemotherapy as treatment of choice for extrapulmonary undifferentiated small cell carcinoma.Cancer, 65: 422–424, 1990.
23.
WadeP.M.Jr., MillsS.E., ReadM., CloudW., LambertM.J. I.I.I., SmithR.E.: Small cell neuroendocrine (oat cell) carcinoma of the breast.Cancer, 52: 121–125, 1983.
24.
WenkR.E., BhagavanB.S., LevyR., MillerD., WeisburgerW.: Ectopic ACTH in prostatic oat cell carcinoma and marked hypernatremia.Cancer, 40: 773–778, 1977.
