A case of transitional cell carcinoma of the bladder displaying prominent signet-ring cell features is reported. Despite combined therapy, the patient died within a few months of the diagnosis, thus confirming the poor prognosis of this tumor. We understand this entity could be considered as an example of neoplastic-associated metaplasia and therefore propose that it should be distinguished from genuine adenocarcinoma.
Get full access to this article
View all access options for this article.
References
1.
BernsteinS.A., ReuterV.E., CarrollP.R., WhitemoreW.F.Jr.,: Primary signet-ring cell carcinoma of the urinary bladder. Urology, 31: 432–436, 1988.
2.
BluteM.L., EngenD.E., TravisW.D., KvolsL.K.: Primary signet ring cell adenocarcinoma of the bladder. J. Urol., 141: 17–21, 1989.
3.
ChoiH., LambS., PintarK., JacobsS.C.: Primary signet-ring cell carcinoma of the urinary bladder. Cancer, 53: 1985–1990, 1984.
4.
De FilippoN., BluteR., KleinL.A.: Signet-ring cell carcinoma of bladder. Evaluation of three cases with review of literature. Urology, 29: 479–483, 1987.
5.
GlobeN.M., ClarkeT.J., TeasdaleC.: Signet-ring cell adenocarcinoma of bladder secondary to long-term catheterization. Urology, 35: 279–281, 1990.
6.
GrignonD.J., RoJ.Y., AyalaA.G., JohnsonD.E.: Primary signet-ring cell carcinoma of the urinary bladder. Am. J. Clin. Pathol., 95: 13–20, 1991.