Two cases of primary cutaneous adenoid cystic carcinoma (ACC) of sweat gland origin are reported. The patients were a 83-year-old man and a 40-year-old woman. Histologically, the neoplasms showed the classic appearence of ACC. CEA, actin and S-100 protein were immunocytochemically demonstrated to be contained in some neoplastic cells. The literature on sweat gland ACC is reviewed and the clinlcopathologic profile of this rare tumor considered.
Get full access to this article
View all access options for this article.
References
1.
BoggioR.: Adenoid cystic carcinoma of the scalp.Arch. Dermatol., 111: 793–794, 1975.
2.
BoggioR.R.: Primary adenoid cystic carcinoma of the skin.Arch. Pathol. Lab. Med., 109: 707, 1985.
HeadingtonJ.T., TeearsR., NiederhuberJ.E., SlingerR.P.: Primary adenoid cystic carcinoma of the skin.Arch. Dermatol., 114: 421–424, 1978.
8.
HoshinoM., YamamotoI.: Ultrastructure of adenoid cystic carcinoma.Cancer, 25: 186–198, 1970.
9.
LennoxB., PearseA.G.E., RichardsH.G.H.: Mucin-secreting tumors of the skin: With special reference to the so-called mixed-salivary tumor of the skin and its relation to hidradenoma.J. Pathol. Bacteriol., 64: 865–880, 1952.
10.
MehreganA.H., HashimotoK., RahbariH.: Eccrine adenocarcinoma. A clinicopathologic study of 35 cases.Arch. Dermatol., 119: 104–114, 1983.
11.
Meyrick-ThomasR.H., LoweB.G., MunroD.D.: Primary adenoid cystic carcinoma of the skin.Clin. Exp. Dermatol., 12: 378–380, 1987.
12.
MillerW.L.: Sweat-gland carcinoma: A clinicopathologic problem.Am. J. Clin. Pathol., 47: 767–780, 1967.
StoutA.P., CooleyS.G.E.: Carcinoma of sweat glands.Cancer, 4: 521–536, 1951.
19.
WickM.R., SwansonP.E.: Primary adenoid cystic carcinoma of the skin. A clinical, histological, and immunocytochemical comparison with adenoid cystic carcinoma of salivary glands and adenoid basal cell carcinoma.Am. J. Dermatopathol., 8: 2–13, 1986.
