Malignant fibrous histiocytoma (MFH) of the upper respiratory tract is rare. We report a case of laryngeal MFH in a 78-year-old man. The patient died 8 months after the first surgical treatment. The clinicopathologic features are described, and the importance of electron microscopy and immunohisto-chemical techniques in the differential diagnosis with so-called « sarcomatoid carcinoma » is stressed. The tumor has an aggressive biological behavior and tends to recur and metastasize.
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