A case is reported of a 76 year old patient with inoperable lymph node metastases from cancer of the penis. Methotrexate and bleomycin chemotherapy and concurrent irradiation were administered. The patient achieved a complete remission and is disease-free 30 months after therapy. The treatment was well tolerated.
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References
1.
AbrattR.P.: The treatment of bilateral ulcerated lymph node metastases from carcinoma of the penis.Cancer, 54: 1720–1722, 1984.
2.
De KernionJ.B., TynbergP., PerskyL., FegenJ.P.: Carcinoma of the penis.Cancer, 32: 1256–1262, 1973.
3.
EdsmyrF., AndersonL., EspostiP.L.: Combined bleomycin and radiation therapy in carcinoma of the penis.Cancer, 56: 1257–1263, 1985.
4.
FraleyE.E., ZhangG., SazamaR., LangeP.H.: Cancer of the penis. Prognosis and treatment plans.Cancer, 55: 1618–1624, 1985.
5.
GarnickM.B., SkarinA.T., SteeleG.D.: Metastatic carcinoma of the penis: complete remission after high dose methotrexate chemotherapy.J. Urol., 122: 265–266, 1979.
6.
IchikawaT., NakanoI., HirokawaI.: Bleomycin treatment of the tumours of the penis and scrotum.J. Urol., 102: 699–708, 1969.
7.
JorgensenS.J.: Experimental bleomycin treatment and combination with radiotherapy in mice.In: Bleomycin in the Treatment of Malignant Disease.Lundbeck, Bedfordshire, U.K., 13–18, 1972.
8.
KyalwazyS.K., BhanaD., HarrisonN.W.: Carcinoma of the penis and bleomycin chemotherapy in Uganda.Br. J. Urol., 46: 689–698, 1974.
9.
LokichJ.J., FreiE.: Phase II study of concurrent methotrexate and bleomycin chemotherapy.Cancer Res., 34: 2240–2242, 1974.
10.
MatheG.: Study of the clinical efficacy of bleomycin in human cancer.Br. Med. J., 2: 643–645, 1970.
11.
MurrellD.S., WilliamJ.L.: Radiotherapy in the treatment of carcinoma of the penis.Br. J. Med., 37: 211–222, 1965.
12.
SklaroffR.B., YagodaA.: Cis-diamminedichloride platinum II (DDP) in the treatment of penile carcinoma.Cancer, 44: 1563–1565, 1979.
13.
SklaroffR.B., YagodaA.: Methotrexate in the treatment of penile carcinoma.Cancer, 45: 214–216, 1980.
