The HID-AB histologic staining technique, which distinguishes sulphomucin from sialomucin types of intestinal metaplasia, was employed in endoscopic gastric mucosal biopsies to evaluate their frequency of association with epithelial dysplasia. Sulphomucin-type intestinal metaplasia was found in 33% of the cases under observation; moderate or severe dysplasia was only associated with this type of intestinal metaplasia. Its precancerous significance can be ascertained only by means of prospective studies.
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References
1.
Arslan PaniniC., BozzolaL.: Precancerous significance of colonic type intestinal metaplasia.Tumori, 67: 113–116, 1981.
2.
JassI.R., FilipeM.I.: A variant of intestinal metaplasia associated with gastric carcinoma: A histochemical study.Histopathology, 3: 191–199, 1979.
3.
JassI.R., FilipeM.I.: Sulphomucins and precancerous lesion of the human stomach.Histopathology, 4: 271–279, 1980.
4.
MatsukuraM., SuzukiK., KawachiT., AoyagiM., SugimuraT., KitaokaH., NumajiriH., ShirotaA., ItabashiM., HirotaT.: Distribution of marker enzymes and mucin in intestinal metaplasia in human stomach and relation of complete and incomplete types of intestinal metaplasia to minute gastric carcinomas.J. Natl. Cancer Inst., 65: 231–236, 1980.
5.
MorsonB.C., SobinL.H., GrundmanE., JohansenA., NagayoT., Serk-HanssenA.: Precancerous conditions and epithelial dysplasia in the stomach.J. Clin. Pathol., 33: 711–721, 1980.
6.
SipponenP., SeppäläK., VarisK., HjeltL., IhamäkiT., KekkiM., SiuralaM.: Intestinal metaplasia with colonie type sulphomucins in the gastric mucosa; its association with gastric carcinoma.Acta Pathol. Microbiol. Scand., A88: 217–224, 1980.
TeglbjaeS., NielsenH.O.: « Small intestinal type » and « colonic type » intestinal metaplasia of the human stomach.Acta Pathol. Microbiol. Scand., A86: 351–355, 1978.
9.
WhiteheadR., TrueloveS.C., GearM.W.: The histological diagnosis of chronic gastritis in fibreoptic gastroscope biopsy specimens.J. Clin. Pathol., 25: 1–11, 1972.
