The presence of carcinoembryonic antigen (CEA)-dependent fluorescence was observed in almost 89% of female genital tract cancers irrespective of their histologic type. Anti-CEA serum was free of antibody to normal cross-reacting antigen. The high percentage of positive fluorescence tests did not correlate with the preoperative serum CEA levels. Double immunodiffusion tests showed different content of CEA and normal cross-reacting antigen in individual specimens of genital tract cancers.
BagshaweK.D., WassM., SearleF.: Glycoproteins in ovarian cancer, pp. 79–87. In: Tumour Markers: Impact and Prospects, BoelsmaE., RümkePh. (Eds.), Vol. 2. Elsevier/North-Holland Biomedical Press, Amsterdam-New York-Oxford, 1979.
3.
BalbierzH., NikolajczukM.: Preparation of immune sera against carcinoembryonic antigen (CEA).Arch. Immunol. Ther. Exp., 26: 231–232, 1978.
4.
BreborowiczJ., MajewskiP.: The radioimmunoassay procedure for quantitative determination of carcinoembryonic antigen (CEA).Ann. Immunol., 6: 55–59, 1974.
5.
CauchiM.N., KohS.H., LimD., HayD.L.: Oncofoetal antigens in cancer of the cervix and ovary.Br. J. Cancer, 44: 403–409, 1981.
6.
DavisB.J.: Disc electrophoresis.II. Method and application to human serum proteins. Ann. N.Y. Acad. Sci., 121: 404–427, 1964.
7.
DonaldsonE.S., van NagellJ.R.Jr., PurseilS., GayE.C., MeekerW.R., KashmiriR., van de VoordeJ.: Multiple biochemical markers in patients with gynecologic malignancies.Cancer, 45: 948–953, 1980.
8.
FordC.H.J., StokesH.J., NewmanC.E.: Carcinoembryonic antigen and prognosis after radical surgery for lung cancer: Immunocytochemical localization and serum levels.Br. J. Cancer, 44: 145–153, 1981.
9.
GoldP., FreedmanS.O.: Demonstration of tumor-specific antigens in human colonic cardinomata by immunological tolerance and absorption techniques.J. Exp. Med., 121: 439–462, 1965.
10.
GoldP., FreedmanS.O.: Specific carcinoembryonic antigens of the human digestive system.J. Exp. Med., 122: 467–481, 1965.
11.
GoldenbergD.M., KimE.E., DeLandF.H., BennettS., PrimusF.J.: Radioimmunodetection of cancer with radioactive antibodies to carcinoembryonic antigen.Cancer Res., 40: 2984–2991, 1980.
12.
GoldenbergD.M., SharkeyR.M., PrimusF.J.: Immunocytochemical detection of carcinoembryonic antigen in conventional histopathology specimens.Cancer, 42: 1546–1553, 1978.
13.
HaegeleP., PetitJ.C., RodierD., JanserJ.C., EberM.: Diagnostic and prognostic use of carcinoembryonic antigen in malignant tumors of the female genital tract. In: Clinical application of carcinoembryonic antigen assay.KrebsB.P., LalanneC.M., SchneiderM. (Eds.), pp. 315–320. Excerpta Medica Amsterdam-Oxford, 1978.
14.
HainesH.G., McCoyJ.P., HofheinzD.E., NgA.B.P., NordquistS.R.B., LeifR.C.: Cervical carcinoma antigens in the diagnosis of human squamous cell carcinoma of the cervix.J. Natl. Cancer Inst., 66: 465–474, 1981.
15.
HarlozinskaA., AlbertW., RogalskiE., RichterR., AlbertZ.: CEA-like antigens in different histologic typse of human lung carcinoma.Neoplasma, 26: 145–156, 1979.
16.
HarlozinskaA., AlbertW., RogalskiE., RichterR., AlbertZ., GawlikowskiW., DomagalaJ.: Immunological reactivity of glycoprotein antigens from human lung cancers.Neoplasma, 27: 641–652, 1980.
17.
IbrahimA.N., RobinsonR.A., MarrL., AbdelalA.T.H., NahmiasA.J.: Tumor-associated antigens in cervical cancer tissues and in sera from patients with cervical cancer or with head and neck cancer.J. Natl. Cancer Inst., 63: 319–323, 1979.
18.
ImamuraN., TakahashiT., LloydK.O., LewisJ.L.Jr., OldL.J.: Analysis of human ovarian tumor antigens using heterologous antisera-detection of new antigenic systems.Int. J. Cancer, 21: 570–577, 1978.
19.
KhooS.K.: Carcinoembryonic antigen in cancer of the female genital tract. A clinical appraisal. In: Clinical Application of Carcinoembryonic Antigen Assay.KrebsB.P., LalanneC.M., SchneiderM. (Eds.), pp. 302–314. Excerpta Medica Asterdam-Oxford, 1978.
20.
LamerzR., BurtinP., SchnablG., LeonhardtA., KümperH.J., SteinG.: Comparative RIA-determinations of CEA serum levels in patients with gynecologic tumors. Use of tracers from different tumor origin. Abstracts of VIIIth Meeting of International Society for Oncodevelopmental Biology and Medicine on Embryonic antigens in cancer, p. 67. Tallinn, USSR, 15th–19th September 1980.
21.
PotomskiJ., HarlozinskaA., StarzykH., RichterR., WozniewskiA.: Correlation between immunohistochemical localization of carcinoembryonic antigen (CEA) and histological estimation of carcinomas, normal mucosae and lymph nodes of the digestive tract in humans.Arch. Immunol. Ther. Exp., 27: 177–186, 1979.
22.
PrimusF.J., ClarkC.A., GoldenbergD.M.: Immunoperoxidase localization of carcinoembryonic antigen in normal human intestinal mucosa.J. Natl. Cancer Inst., 67: 1031–1039, 1981.
23.
SchevchukM.M., FenoglioC.M., RichartR.M.: Carcinoembryonic antigen localization in benign and malignant transitional epithelium.Cancer, 47: 899–905, 1981.
24.
WagenerC., Müller-WallrafR., NissonS., GrönerJ., BreuerH.: Localization and concentration of carcinoembryonic antigen (CEA) in gastrointestinal tumors: Correlation with CEA levels in plasma.J. Natl. Cancer Inst., 67: 539–547, 1981.
25.
WahlströmT., LindgrenJ., SeppäläM.: Presence of carcinoembryonic antigen in tumor cells lacks prognostic significance in epidermoid carcinoma of the uterine cervix. In: Carcino-Embryonic Proteins, LehmannF.G. (Ed.), Vol. 2, pp. 181–183. Elsevier/North-Holland Biomedical Press, 1979.
26.
WeberK., OsbornM.: The reliability of molecular weight determination by dodecyl sulfate-polyacrylamide gel electrophoresis.J. Biol. Chem., 244: 4406–4412, 1969.
27.
ZawadzkaH., LisowskaE., HarlozinskaA., AlbertZ., RichterR., JanuszM.: Differences in the purification effect of carcinoembryonic antigen (CEA) from the three different hepatic metastases of rectum carcinoma.Neoplasma, 26: 157–167, 1979.