Atypical Reserve Cell Hyperplasia of Cervical Glands,Simulating Adenocarcinoma. An Undescribed Reversible Lesion in a Woman Taking Oral Contraceptives

Abstract

Italian

On the basis of a characteristic lesion of the endocervical mucosa in a woman who had taken contraceptives for 4 years, the authors review the problem of these alterations, also in light of their personal experience.

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References

Candy Abell

M.R.

: Progestogen-induced adenomatous hyperplasia of the uterine cervix. J.A.M.A., 203: 85–88, 1968.

Czemobilsky

: Morphological changes in the cervix and vagina induced by combined hormonal medication. In: Dallenbach-Hellweg

: Functional Morphologic Changes in Female Sex Organs Induced by Exogenous Hormones, p. 191. Springer-Verlag, Berlin, 1980.

Dallenbach-Hellweg

: Morphological changes induced in the human uterus and Falloppian tube by exogenous estrogens. In: Dallenbach-Hellweg

: Functional Morphologic Changes in Female Sex Organs Induced by Exogenous Hormones, p. 39. Springer-Verlag, Berlin, 1980.

Epperson

J.W.W.

Hellman

Galvin

Busby

: The morphological changes in the cervix during pregnancy, including intraepithelial carcinoma. Am. J. Obstet. Gynecol., 61: 50–61, 1951.

Ferenczj

: Anatomy and histology of the cervix. In: Blaunstein A.: Pathology of Female Genital Tract, p. 102. Springer-Verlag, Berlin, 1977.

Fluhmann

C.F.

: A clinical and histopathological study of lesions of the cervix during pregnancy. Am. J. Obstet. Gynecol., 55: 133–147, 1948.

Gall

S.A.

Bourgeois

Maguire

: The morphologic effect of oral contraceptive agents on the cervix. J.A.M.A., 207: 2243–2247, 1969.

Graham

C.E.

Uterine cervical epithelium of fetal and immature human females in relation to estrogenic stimulation.

Am. J. Obstet. Gynecol., 97: 1033–1040, 1967.

Hellman

L.M.

Rosenthal

A.H.

Kistner

R.W.

Gordon

: Some factors influencing the proliferation of the reserve cells in the human cervix. Am. J. Obstet. Gynecol., 67: 899–915, 1954.

10.

Johnson

L.D.

: Carcinoma in situ in pregnancy. In: The Uterus, p. 382, Williams and Wilkins, Baltimore, 1973.

11.

Kraus

F.T.

: The biology of carcinoma in situ and microinvasive carcinoma of the cervix. In: The Uterus, p. 348, Williams and Wilkins, Baltimore, 1973.

12.

Kyriakos

Richard

Kempson

R.L.

Konikov

N.F.

: A clinical and pathologic study of endocervical lesions associated with oral contraceptives. Cancer, 22: 99–110, 1968.

13.

Maqueo

Azuela

C.I.

Calderon

J.J.

Goldzieher

J.W.

: Morphology of the cervix in women treated with synthetic progestins. Obstet. Gynecol., 96: 994–998, 1966.

14.

Nichols

T.M.

Filder

H.K.

: Microglandular hyperplasia in cervical cone biopsies taken for suspicious and positive cytology. Am. J. Clin. Pathol., 56: 424–429, 1971.

15.

Schaude

Dallenbach-Hellweg

Schlafer

: Histologic changes of the cervix uteri following contraceptive use. In: Dallenbach-Hellweg: Functional Morphologic Changes in Female Sex Organs Induced by Exogenous Hormones, p. 191. Springer-Verlag, Berlin, 1980.

16.

Siiteri

P.K.

MacDonald

P.C.

: Role of extraglandular estrogens in human endocrinology. In: Geiger

S.R.

Astwood

E.B.

and Greep

R.O.

(eds.): Handbook of Physiology. Sect. 7,2. p. 615. N.Y. Am. Phys. Soc., 1973.

17.

Siiteri

P.K.

: Steroid hormones and endometrial cancer. Cancer Res., 38: 4360–4366, 1978.

18.

Taylor

H.B.

Irey

Norris

J.H.

: Atypical endocervical hyperplasia in women taking oral contraceptives. J.A.M.A., 202: 185–187, 1967.