The total concentration of protein suifhydryl (SH) groups was determined in the sera of 15 patients with untreated malignant lymphoma (4 patients with Hodgkin's disease and 11 with non-Hodgkin's malignant lymphoma) using 5,5'-dithiobis (2-nitrobenzoic acid) (DTNB). Serum SH total concentration in all patients was markedly depressed and significantly lower than that observed in the sera of healty controls matched for sex and age.
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