One hundred-fifty-five cervical carcinomas were classified according to the Wentz and Reagan (21) cyto-histological system, and correlated to 5 year survival rates. This classification subdivides epidermoid carcinomas into three sub-groups: keratinizing carcinoma, large cell carcinoma, and small cell carcinoma. No significant differences between one group and another were observed. The importance of the type of therapy in conditioning the significance of this classification system is discussed.
Get full access to this article
View all access options for this article.
References
1.
BlomfieldG.W.CherryC.P.GlucksmannA.: Biological factors influencing the radiotherapeutic results in carcinoma of the cervix.Br. J. Radiol., 38: 241–254, 1965.
2.
BougleR.BergerM.LevinM.: Variations in the morphogenesis of squamous carcinoma of the cervix.Cancer, 16: 1151–1159, 1963.
3.
CharbitA.MalaiseE.P.TubianaM.: Relation between the pathological nature and the growth rate of human tumors.Eur. J. Cancer, 7: 307–315, 1971.
4.
EagenR.T.MaurerL.H.ForcierR.J.TullahM.: Small cell carcinoma of the lung-staging, paraneoplastic syndromes, treatment and survival.Cancer, 33: 527–532, 1974.
5.
FinckF.M.DenkM.: Cervical carcinoma: Relationship between histology and survival following radiation therapy.Obstet. Gynecol., 35: 339–343, 1970.
6.
GoellnerJ.R.: Carcinoma of the cervix.Clinicopathologic correlation of 196 cases. Am. J. Clin. Pathol., 66: 775–785, 1976.
7.
GundersonL.L.WeemsW.S.HebertsonR.M.PlenkH.P.: Correlation of histopathology with clinical results following radiation therapy for carcinoma of the cervix.Am. J. Roentgenol. Radium Ther. Nucl. Med., 120: 74–86, 1974.
8.
MalaiseE.P.ChavaudraN.TubianaM.: The relationship between growth rate, labelling index and histological type of human solid tumors.Eur. J. Cancer, 9: 305–312, 1973.
9.
van NagellJ.R.DonaldsonE.S.WoodE.G.MaruyamaY.UtleyJ.: Small cell cancer of the uterine cervix.Cancer, 40: 2243–2249, 1977.
10.
NenciI.Arslan PagniniC.: Criteri morfologici per la prognosi del carcinoma mammario.Riv. Pat. Clin. Sper., 14: 105–134, 1974.
11.
NgA.B.P.AtkinN.B.: Histological cell type and DNA value in the prognosis of squamous cell cancer of uterine cervix.Br. J. Cancer, 28: 322–331, 1973.
12.
Nødskov-PedersenS.: Degree of malignancy of cancer involving the cervix uteri, judged on the basis of clinical stage, histology, size of nuclei, and content of DNA.Acta Pathol. Microbiol. Scand., 79: 617–628, 1971.
ReaganJ.W.NgA.B.P.WentzW.B.: Concepts of genesis and development in early cervical neoplasia.Obstet. Gynecol. Survey, 24: 860–874, 1969.
15.
SidhuG.S.KossL.G.BarberH.R.K.: Relation of histologic factors to the response of stage I epidermoid carcinoma of the cervix to surgical treatment.Analysis of 115 patients. Obstet. Gynecol., 35: 329–338, 1970.
16.
SwanD.S.RoddickJ.W.: A clinical-pathological correlation of cell type classification for cervical cancer.Am. J. Obstet. Gynecol., 116: 666–670, 1973.
17.
TerzJ.J.CurutchetH.P.LawrenceW.: Analysis of the cell kinetics of human solid tumors.Cancer, 28: 1472–1478, 1971.
18.
WalterL.GlucksmannA.CherryC.P.: Biological and physical factors in the radiotherapy of carcinoma of the cervix.J. Obstet. Gynaecol. Br. Commonw., 72: 575–585, 1965.
19.
WentzW.B.: Histologic grade and survival in cervical cancer.Obstet. Gynecol., 18: 412–416, 1961.
20.
WentzW.B.LewisG.C.: Correlation of histologic morphology and survival in cervical cancer following radiation therapy.Obstet. Gynecol., 26: 228–232, 1965.
21.
WentzW.B.ReaganJ.W.: Survival in cervical cancer with respect to cell type.Cancer, 12: 384–388, 1959.
