A new classification scheme for malignant tumors of the nasopharynx is proposed in which the undifferentiated carcinoma of nasopharyngeal types as a prominent position. This term replaces the previous obsolete term lymphoepithelioma on the basis of its clinicopathologic identity, its separation from squamous cell carcinoma, and its potential origin from anatomical areas other than the nasopharynx.
Get full access to this article
View all access options for this article.
References
1.
BrugèreJ., BlacheR., CachinY.: Draft recommendations for future studies.International Symposium on the Etiology and Control of Nasopharyngeal Carcinoma, Kyoto (Japan), April 4–6, 1977.
2.
BrugèreJ., BlacheR., CachinY.: International Classification of Diseases for Oncology. 1st Ed. W.H.O., Geneva, 1976.
3.
BrugèreJ., BlacheR., CachinY.: Extension métastasique des épithéliomas épidermoïdes des voïes aéro-digestives supérieures: bilan de l'autopsie de 220 malades. Bull. Cancer, 59: 435–448, 1972.
4.
CommounM., HoernerG. V., MouraliN.: Tumors of the nasopharynx in Tunisia. An anatomic and clinical study based on 143 cases. Cancer, 33: 184–192, 1974.
5.
ChenK. Y., FletcherG. H.: Malignant tumors of the nasopharynx. Radiology, 99: 165–171, 1971.
6.
MicheauC.: Anatomie pathologique et essai de classification des épithéliomas du naso-pharynx. Bull. Cancer, 62: 277–286, 1975.
7.
MicheauC., LuboinskiB., SchwaabG., RichardJ., CachinY.: Lympho-epitheliomas of the larynx (undifferentiated carcinomas of naso-pharyngeal type); a report of 3 cases. Clin. Otolaryngol. (in press).
8.
RegaudC., ReverchonL.: Sur un cas d'épithélioma épidermoïde développé dans le massif maxillaire supérieur, étendu aux téguments de la face, aux cavités buccale, nasale et orbitaire, ainsi qu'aux ganglions du cou, guéri par la curiethérapie. Rev. Laryngol., 42: 369–378, 1921.
9.
RilkeF., PilottiS.: Die zytologische Diagnose der Epipharynxkarzinome. Verh. Dtsch. Ges. Pathol., 57: 373–388, 1973.
10.
RilkeF., PilottiS., ClementeC., MolinariR.: Le diagnostic cytologique et les corrélations cyto-histologiques des tumeurs épithéliales malignes du rhino-pharynx. Bull. Cancer, 62: 287–294, 1975.
11.
ScanlonP. W., RhodesR. E.Jr., WoolnerL. B., DevineK. D., McBeanJ. B.: Cancer of the nasopharynx, 142 patients treated in the 11 year period 1950–1960. Am. J. Roentgenol., 99: 313–325, 1967.
ShanmugaratnamK.: Cancer of the nasopharynx. In Proceedings of the Ninth International Cancer Congress. UICC Monograph Series, Vol. 10, pp. 110–116. HarrisR. J. C. (ed.). Springer-Verlag, Berlin, Heidelberg, 1967.
14.
ShanmugaratnamK.: International histological classification of tumors (no. 19). Histological typing of upper respiratory tract tumors. World Health Organization, Geneva, 1978.
15.
SvobodaD., KirchnerF., ShanmugaratnamK.: The fine structure of nasopharyngeal carcinoma. In: Cancer of the Nasopharynx. UICC Monograph Series. Vol. 1, pp. 163–171. MuirC. S., ShanmugaratnamK. (eds.). Munksgaard, Copenhagen, 1967.
16.
WangC. C., LittleJ. B., SchulzM. D.: Cancer of the nasopharynx. Its clinical and radiotherapeutic considerations. Cancer, 15: 921–926, 1962.
17.
YehS.: A histological classification of carcinomas of the nasopharynx with a critical review as to the existence of lymphoepitheliomas. Cancer, 15: 895–920, 1962.