Personal experience of Technetium-99m-sulfur colloid in the scintiscanning of bone marrow is reported. The method offers technical advantages over other methods and superior protection, while its only limitation is that it does not permit a dynamic study of hematopoiesis. Four pathologic scans typical of four groups of diseases may be distinguished. Further, metastatic bone marrow localisations can be diagnosed much earlier and more precisely than by radiography.
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References
1.
AngerH. O., Van DykeD. C.: Human bone marrow distribution shown in vivo by Fe-52 and positron scintillation camera.Science, 144: 1587–1589, 1964.
2.
BellE. G., McAfeeJ. G., ConstableW. C.: Local radiation damage to bone and marrow demonstrated by radioisotopic imaging.Radiology, 92: 1083–1088, 1969.
3.
Du SaultL. A., ShawR. A., EylerW. R.: Tc-99m sulfide colloid scanning for bone lesions.Radiology, 94: 161–166, 1970.
4.
EdwardsC. L., AndrewsG. A., SittersonB. W., KniseleyR. M.: Clinical bone marrow scanning with radioisotopes.Blood, 23: 741–755, 1964.
5.
EngstedtL., FranzenS., JonssonL., LarssonL. G.: In vivo localization of colloidal Au-198 intravenously injected in polycythemia vera.Acta Radiol., 49: 66–72, 1958.
6.
EngstedtL., FranzenS., JonssonL., LarssonL. G.: Reticuloendothelial activity studied in vivo in humans by means of whole body scintigrama after intravenous injection of colloidal Au-198.HellerJ. H. (ed.), Intern. Soc. Res. R.E.S.,221–232. 3° Simp. Rapallo, Agosto1958.
7.
GoswitzF. A., EdwardsC. L., VodopickH.: Assessment of erythropoiesis by ferrokinetics and radiocolloid bone-marrow scanning.J. Nucl. Med.,9: 319, 1968.
KniseleyR. M., AndrewsG. A., TanidaR., EdwardsC. L., KykerG. C.: Delineation of active marrow by whole-body scanning with radioactive colloids.J. Nucl. Med., 7: 575–582, 1966.
10.
LarsonS. M., NelpW. B.: Radiopharmacology of a semplified Tc-99m colloid preparation for photoscanning.J. Nucl. Med., 7: 817–822, 1966.
11.
NelpW. B., LarsonS. M., LewisR. J.: Distribution of the erythron and the RES in the bone marrow organ.J. Nucl. Med., 8: 430–436, 1967.
12.
RainJ. D., DreschC., NajeanY.: Bilan actuel des études scintigraphiques de la moelle osseuse.Nouv. Rev. Franç. Hémat., 3: 390–397, 1973.
13.
Van DykeD. C., AngerH. O.: Patterns of marrow hypertrophy and atrophy in man.J. Nucl. Med., 6: 109–120, 1965.