Abstract
Absorbed serum from a rabbit immunized with an extract of a pool of 5 breast carcinomas yielded a single precipitation line when tested on the pooled tumors used to immunize and on single breast carcinomas, whether participating in the immunization or not. No precipitation was seen with control normal mammary tissues from the same patients. Antisera from 5 out of 9 rabbit immunized with different single breast carcinomas gave one precipitin line against the tumor used to immunize and also in cross-reaction against the other 4 mammary carcinomas positive in the direct test. No bands were obtained with normal mammary tissue extracts or with a fibroadenoma extract. A rabbit antiserum against the fibroadenoma was always negative on all the breast carcinoma extracts tested.
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