Abstract
Serum immunoglobulins of lymphomas were studied with electrophoresis and immunodiffusion. A new method was employed for electrophoresis study, which exploiting the shape of the particles, allows to obtain numerous and precise fractions. In the gammaglobulins region of two cases it was possible to recognize paraproteins-like components that could not be identified with other methods. In the same two cases, alterations in the immunoelectrophoretic pattern were noted, while in other 47 lymphomas no immunoelectrophoretic alterations were recognized. The quantitative determination of the Ig-globulins was studied in 60 cases with the immunodiffusion technique. A disbalance between the three main classes of immunoglobulins was noted in all types of lymphomas whether of lymphocitic or reticular origin. In most cases the Ig G and Ig A were increased and Ig M reduced.
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