Considerations on the value of scintillation scanning of the spleen, using Cr51 and BMHP-Hg197 labelled red cells, in neoplastic diseases and particularly in malignant lymphomas are reported. The examination was performed in 45 patients and was found useful for the demonstration of changes in spleen size and morphology and for differential diagnosis with abdominal masses. Splenomegalies were studied also through the index of splenic surface. It was also possible the demonstration of « cold areas », corresponding to intrasplenic alterations, as neoplastic infiltration.
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