Abstract
Immunoelectrophoretic changes in the serum of 32 patients with various type of malignant tumors, were studied. The method described by Grabar and Burtin was used. The following results were obtained: Albumin: The line of precipitation was in all cases more curved, less intensive and generally shortened; Alpha-1 globulin: The curves found were well visible and symmetrical in both pathological and control sera; Alpha-2 globulin: The line of alpha-2 macroglo-bulins was always present and best marked; Beta-1 globulin: Always well visible the line of siderophyllin. Under this line, in 14 out of 32 cases, a line, which is presumably beta-1/A globulin, was found; Beta-2 globulin: In half of the cases the line of beta-2/M was well visible; Gamma-globulin: No changes were found. The changes found are believed to be related to the reaction of normal, serum proteins producing cells to the presence of malignant tumors.
Get full access to this article
View all access options for this article.