Abstract
Referring to a previous paper, it is stated that in some cases a progestonal activity may subsist in the follicular phase of the menstrual cycle. This progestonal activity is supposed to inhibit the corpus luteum development of the actual cycle. In fact in these cases the basal body temperature is observed to be of irregular type and the endometrium shows a mixed folliculo-progestional picture. Vaginal smears do not show signs of an efficient luteinic activity.
In such cases, the stimulating action of the LTH hormone, alone or associated with prolactin, does not modify the picture observed before treatment. A modification is obtained only by a previous gonadotropic stimulation in suitable doses and during the follicular phase.
In cases in which the progestional activity is deficient and of short duration but the first phase of the cycle is not troubled by a persisting progestional activity, the highest secretory response is obtained by prolactin administered during the second half of the cycle (endometrial picture similar to that of initial pregnancy, vaginal smear with intense activity of the basophilic elements, prolongation of the secretory phase of the cycle). 2 out of 4 cases who underwent this treatment recovered even from sterility.
Get full access to this article
View all access options for this article.