Abstract
Spontaneous mammary adenocarcinoma and methylcholanthrene sarcoma were transplanted into mice bearing sarcoma 180. An increase of basophilia was observed in the liver cells and is described at different time intervals after transplantation. Such increase is due to ribonucleoproteins and has been demonstrated by means of a modified Giemsa method, here described. The meaning of the phenomenon is discussed, basing on the present knowledge about liver changes induced by tumours. The obtained data suggest the hypothesis that some substances released by the tumour may enter into circulation, causing an alteration of the liver metabolism (consisting in a prevalence of the reproductive phenomena on the functional ones).
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