Abstract
Introdution:
Reactive eosinophilia has been reported in several hematological malignancies, including Hodgkin–s lymphoma, T-cell lymphoma/leukemia, and acute leukemia. However, eosinophilia associated with B-cell non-Hodgkin–s lymphoma is rarely reported. Mantle cell lymphoma is a subcategory of non-Hodgkin–s lymphoma originated from mature B cells. In this article, we report for the first time a case of mantle cell lymphoma with hypereosinophilia.
Case description:
A 69-year-old male patient was diagnosed with mantle cell lymphoma accompanied by eosinophilia, with common secondary causes of eosinophilia ruled out. Following immunochemotherapy, the patient achieved lymphoma remission, and eosinophil levels returned to normal.
Conclusion:
This case potentially adds to the limited body of literature on eosinophilia in B-cell non-Hodgkin lymphoma. The limitations of this study include the absence of expanded genetic panel testing to confirm eosinophil clonality or T-cell clonality, unmeasured IL-5 levels, and inherent constraints of case reports.
Get full access to this article
View all access options for this article.
References
Supplementary Material
Please find the following supplemental material available below.
For Open Access articles published under a Creative Commons License, all supplemental material carries the same license as the article it is associated with.
For non-Open Access articles published, all supplemental material carries a non-exclusive license, and permission requests for re-use of supplemental material or any part of supplemental material shall be sent directly to the copyright owner as specified in the copyright notice associated with the article.
