Drug-induced immune thrombocytopenia may occur secondary to several chemotherapeutic agents or new targeted monoclonal antibodies, but thrombocytopenia induced by trastuzumab is a very rare occurrence. We report a case of severe thrombocytopenia related to the administration of trastuzumab six months after the first exposure.
ParikhO., NeaveF., PalmieriC.: Severe thrombocytopenia induced by a single infusion of trastuzumab.Clin Breast Cancer, 8: 285–286, 2008.
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SáncehzC.J., GárateC., JiménezJ.G.D., PárragaJ.P.: Drug-induced thrombocytopenia induced by trastuzumab: a special challenge in a curable disease.Ann Oncol, 20: 1607–1608, 2009.