Abstract
An 82-year-old non-smoker female was admitted with cough, fever and poor general health.
Radiological examination revealed a right parahilar mass and a transbronchial biopsy confirmed the presence of a tumor. Immunohistochemical analysis established the diagnosis of high-grade primary pulmonary lymphoma. The rare nature of this disease, its non-specific clinical presentation and particular prognosis, also in elderly patients, are discussed in this article.
Get full access to this article
View all access options for this article.
References
1.
Isaacson
P.G.
,
Norton
A.J.
: Extranodal lymphomas. Churchill Livingstone , New York , 1994 .
2.
Habermann
T.H.
,
Ryu
J.H.
,
Inwards
D.J.
,
Kurtin
P.J.
: Primary pulmonary lymphoma . Semin Oncol , 26 : 307 –315 , 1999 .
3.
L'Hoste
R.J.
Jr.
,
Filippa
D.A.
,
Lieberman
P.H.
,
Bretsky
S.
: Primary pulmonary lymphomas. A clinicopathologic analysis of 36 cases . Cancer , 54 : 1397 –1406 , 1984 .
4.
Cadranel
J.
,
Wislez
M.
,
Antoine
M.
: Primary pulmonary lymphoma . Eur Respir J , 20 : 750 –762 , 2002 .
5.
Isaacson
P.G.
: Mucosa-associated lymphoid tissue lymphoma . Semin Haematol , 36 : 139 –147 , 1999 .
6.
Kim
J.H.
,
Lee
S.H.
,
Park
J.
,
Kim
H.Y.
,
Lee
S.I.
,
Park
J.O.
,
Kim
K.
,
Kim
W.S.
,
Jung
C.W.
,
Park
Y.S.
,
Im
Y.H.
,
Kang
W.K.
,
Lee
M.H.
,
Park
K.
,
Han
J.H.
,
Ko
Y.H.
: Primary pulmonary non-Hodgkin's lymphoma . Jpn J Clin Oncol , 34 : 510 –514 , 2004 .
7.
Fiche
M.
,
Caprons
F.
,
Berger
F.
,
Galateau
F.
,
Cordier
J.F.
,
Loire
R.
,
Diebold
J.
: Primary pulmonary non-Hodgkin's lymphomas . Histopathology , 26 : 529 –537 , 1995 .
8.
Li
G.
,
Hansmann
M.L.
,
Zwingers
T.
,
Lennert
K.
: Primary lymphomas of the lung: morphological, immunohistochemical and clinical features . Histopathology , 16 : 519 –531 , 1990 .
9.
Martin
A.
,
Capron
F.
,
Liguory-Brunaud
M.D.
,
De Frejacques
C.
,
Pluot
M.
,
Diebold
J.
: Epstein-Barr virus-associated primary malignant lymphomas of the pleural cavity occurring in longstanding pleural chronic inflammation . Hum Pathol , 25 : 1314 –1318 , 1994 .
10.
Cordier
J.F.
,
Chailleux
E.
,
Lauque
D.
,
Reynaud-Gaubert
M.
,
Dietemann-Molard
A.
: Primary pulmonary lymphomas. A clinical study of 70 cases in nonimmunocompromised patients . Chest , 103 : 201 –208 , 1993 .
11.
Cattelani
L.
,
Solli
P.
,
Rusca
M.
,
Carbognani
P.
,
Spaggiari
L.
,
Gabrielli
M.
,
Bobbio
P.
: Primary pulmonary lymphoma: report of a case diagnosed by transbronchial biopsy . J Cardiovasc Surg , 37 : 539 –541 , 1996 .
12.
Zinzani
PL
,
Gherlinzoni
F.
,
Storti
S.
,
Zaccaria
A.
,
Pavone
E.
,
Moretti
L.
,
Gentilini
P.
,
Guardigni
L.
,
De Renzo
A.
,
Fattori
P.P.
,
Falini
B.
,
Lauta
V.M.
,
Mannina
D.
,
Zaja
F.
,
Mazza
P.
,
Volpe
E.
,
Lauria
F.
,
Aitini
E.
,
Ciccone
F.
,
Tani
M.
,
Stefoni
V.
,
Alinari
L.
,
Baccarani
M.
,
Tura
S.
: Randomized trial of 8-week versus 12-week VNCOP-B plus G-CSF regimens as front-line treatment in elderly aggressive non-Hodgkin's lymphoma patients . Ann Oncol , 13 : 1364 –1369 , 2002 .