Acute pretreatment tumor lysis syndrome is a rare complication of cancer. Early recognition and aggressive management are mandatory for prevention of the adverse sequelae of the syndrome. Here we present 2 cases of pretreatment tumor lysis syndrome, concluding that this clinical entity should be in the differential diagnosis of acute renal failure associated with malignancy, as early recognition is in fact the mainstay of treatment.
BaeksgaardL., SorensenJ.B.: Acute tumor lysis syndrome in solid tumors - a case report and review of the literature.Cancer Chemother Pharmacol, 51: 187–192, 2003.
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HsuH.H., ChanY.L., HuangC.C.: Acute spontaneous tumor lysis presenting with hyperuricemic acute renal failure: clinical features and therapeutic approach.J Nephrol, 17: 50–56, 2004.
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HsuH.H., HuangC.C.: Acute spontaneous tumor lysis in anaplastic large T-cell lymphoma presenting with hyperuricemic acute renal failure.Int J Hematol, 79: 48–51, 2004.