Hematogenous retinal metastases from non-small cell lung cancer are rare, and are even more uncommonly observed bilaterally. Non-small cell lung cancer usually metastasizes to the liver, adrenal glands, lung, bone, central nervous system, and kidney. We report the case of a 41-year-old male patient with advanced lung adenocarcinoma heavily pretreated with polychemotherapy and palliative radiotherapy up to June 2003, when synchronous bilateral retinal metastases were diagnosed. The patient's prognosis was worsened by the onset of the retinal metastases and he died three months later.
AuerbachO., GarfunkelL., ParksV.R.: Histologic type of lung cancer in relation to smoking habits, year of diagnosis and sites of metastases. Chest, 67: 382–387, 1975.
2.
MatthewsM.J.: Problems in morphology and behaviour of broncopulmonary malignant disease. In: Lung cancer: natural history, prognosis and therapy, IsraelL., ChahanianP. (Eds), pp 23–62, Academic Press, New York, 1976.
3.
OnuigboW.I.B.: Patterns in metastasis in lung cancer: a review. Cancer Press, 21: 1077–1085, 1961.
4.
CangiarellaJ.F., SuhrlandM.J., CajigasA., ChessJ., KossL.G., BerkowitzD., SchlesingerK.: Esophageal carcinoma metastatic to the retina. Diagnosis of a case by cytologic examination of intraocular vitreous washings. Acta Cytol, 40: 995–998, 1996.
5.
MackH.G., JakobiecF.A.: Isolated metastases to the retina or optic nerve. Int Ophthalmol Clin, 37: 251–260, 1997.
