Sixty-seven patients with malignant melanomas were seen in our institute since 1998. We looked for a sentinel node in 26 (38%) patients with lesions thicker than 1 mm, employing a double technique: staining with methylene blue and gamma probe mapping after injection of 99mTc. Forty-six nodes were retrieved, 25% of them containing tumor cells. This approach enabled us to choose between a wait-and-see policy and radical surgery.
BostikP., EssnerR., SarantouT.: Intraoperative lympatic mapping for early stage melanoma of the head and neck.Am. J. Surg., 174: 536–539, 1997.
3.
CascinelliN., MorabitoA., SantinamiN.: Immediate or delayed dissection of regional nodes in patients with melanoma of the trunk: a randomized trial.Lancet, 351: 793–796, 1998.
4.
MortonD.L., WenD.R., CochranA.J.: Management of early stage melanoma by intraoperative lympatic mapping and selective lymphadenectomy: an alternative to routine lymphadenectomy or “watch and wait”.Surg. Oncol. Clin. Am., 1: 247–259, 1992.
5.
ParkerS.L., TongT., BoldenS.: Cancer statistics.CA Cancer J. Clin., 46: 5–27, 1996.
6.
Schraffordt KoopsH., PiersD.A., TieboschA.T.M.G.: Sentinel node biopsy in melanoma of the skin.Eur. J. Nucl. Med.,26 Suppl., S 02–02, 1999.
7.
SimF.H., TaylorW.P., PritchardD.J.: Lymphadenectomy in the management of stage I malignant melanoma: a prospective randomized study.Mayo Clin. Proc, 61: 697–705, 1986.
8.
Van der VeenH., HoekstraO.S., PaulM.A.: Gamma probe-guided sentinel node biopsy to select patients with melanoma for lymphadenectomy.Br. J. Surg., 81: 1769–1770, 1994.
