Comparison of the Efficacy of Furosemide with Two Furosemide-Triamterene Combinations in the Treatment of Cardiac Insufficiency

Abstract

Nine patients suffering from cardiac insufficiency were given furosemide and two furosemide-triamterene combination products in random order. A statistically significant diuretic response was achieved with all these preparations. The combination of furosemide and triamterene brought about a ‘softer’ diuresis, no hypokalemia and the advantage of dosage as only one tablet, thus eliminating the need for taking two separate drugs.