A double-blind study, carried out at two centres, comparing once and twice a day application of betamethasone-17, 21-dipropionate cream 0·05% (Diproderm®), has shown that the efficacy in treating eczema is the same after 1 week.
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References
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NordwallC (1974) Local treatment of psoriasis and eczema with betamethasone-17, 21-dipropionate (Diproderm cream): A double-blind comparison with fluocortolone caproate, fluocortolone pivalate (Ultralanum cream). Current Therapeutic Research, 16, 8, 798.
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VoigtlanderV (1977) A clinical comparison of betamethasone-17, 21-dipropionate and clobetasol propionate creams in dermatology. The Journal of International Medical Research, 5, 2, 128.