An Open Study of Pivampicillin (Pondocillin) as a Treatment for Acute Lower Urinary Tract Infection

Abstract

In a multicentre general practice study 158 females with acute, uncomplicated urinary tract infection received a 5-day course of pivampicillin 500 mg twice-daily (Pondocillin). Significant bacteriological cultures were obtained from forty-one patients before treatment and the original organism was eradicated in thirty-eight of these patients (93%). The mean symptom score was reduced from 7·33 to 1·18. Eleven patients (7%) reported side-effects. One patient ceased treatment after 4 days due to a rash. Pivampicillin, in a convenient twice-daily regimen, was confirmed as an effective treatment for acute lower urinary tract infection.