Fifty-seven general practice patients (fifty-five females and two males) with acute uncomplicated cystitis received a 5-day course of pivmecillinam suspension at a dose of 200 mg (2 sachets) three times a day. Positive bacteriological cultures were obtained from twenty-eight patients (49%) before treatment. The bacteriological cure rate was 100%. All patients experienced some relief of symptoms and thirty nine patients (68%) were completely symptom-free after treatment.
Selexid suspension was generally well tolerated. Side effects were reported in only four patients (6%) and no patient had to stop treatment prematurely.
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References
1.
AaraasISkarstenK WNeessH C (1977) Pivmecillinam in the treatment of post-operative bacteriuria in gynaecological patients. A double-blind comparison with pivampicillin. Journal of Antimicrobial Chemotherapy3, 227.
2.
BentzenA JVejlsgaardRJacobsenJTybringL (1975) Clinical evaluations of a novel beta-lactam antibiotic: pivmecillinam (F.L.1039). Infection3, 154.
3.
BreskyB (1977) Controlled randomized study comparing amoxycillin and pivmecillinam in adult out-patients presenting with symptoms of acute urinary tract infection. Journal of Antimicrobial Chemotherapy3, (Suppl B), 121.
4.
BrumfittWFranklinIHamilton-MillerJAndersonF (1979) Comparison of pivmecillinam and cephradine in bacteriuria in pregnancy and in acute urinary tract infection. Scandinavian Journal of Infectious Diseases11, 275.
5.
DonaldJ FRimmerD M D (1980) An open evaluation of a 3-day course of pivmecillinam (ten 200 mg tablets) in women with acute uncomplicated cystitis. Journal of International Medical Research8, 112.
6.
GuttmannD (1977) A comparison of pivmecillinam and co-trimoxazole in the treatment of simple cystitis in general practice. Journal of Antimicrobial Chemotherapy3, (Suppl B), 137.
7.
IshigamiJ (1977) Clinical evaluation of pivmecillinam in acute simple cystitis: a comparative study with amoxycillin by a randomized double-blind technique. Journal of Antimicrobial Chemotherapy3, (Suppl B), 129.
8.
MarshB TMendayA P (1980) Comparative efficacy of 3-day and 7-day chemotherapy with pivmecillinam in urinary tract infections in general practice. Journal of International Medical Research8, 105.
9.
JonesE R VerrierAsscherA W (1975) Treatment of recurrent bacteriuria with pivmecillinam. Journal of Antimicrobial Chemotherapy1, 193.
